| Literature DB >> 6896115 |
B B Vargaftig, J Lefort, R C Murphy.
Abstract
Branchoconstriction in the guinea-pig due to leukotrienes C4 and D4 in vivo and in vitro was suppressed by aspirin. Since contracting effects of putative mediators of bronchial asthma should be refractory to inhibition of cyclooxygenase, our results indicate that release of leukotrienes in the guinea-pig does not alone account for anaphylactic bronchoconstriction.Entities:
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Year: 1981 PMID: 6896115 DOI: 10.1007/bf01978747
Source DB: PubMed Journal: Agents Actions ISSN: 0065-4299