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Literature DB >> 6895890

Trioxacarcins, novel antitumor antibiotics. I. Producing organism, fermentation and biological activities.

F Tomita, T Tamaoki, M Morimoto, K Fujimoto.

Abstract

Entities: Chemical

Mesh：

Substances：

Year: 1981 PMID： 6895890 DOI： 10.7164/antibiotics.34.1519

Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649

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17 in total

1. Diastereoselective additions of allylmetal reagents to free and protected syn-α,β-dihydroxyketones enable efficient synthetic routes to methyl trioxacarcinoside A.

Authors: Daniel J Smaltz; Jakub Švenda; Andrew G Myers
Journal: Org Lett Date: 2012-03-09 Impact factor: 6.005

Review 2. Taxonomy, Physiology, and Natural Products of Actinobacteria.

Authors: Essaid Ait Barka; Parul Vatsa; Lisa Sanchez; Nathalie Gaveau-Vaillant; Cedric Jacquard; Jan P Meier-Kolthoff; Hans-Peter Klenk; Christophe Clément; Yder Ouhdouch; Gilles P van Wezel
Journal: Microbiol Mol Biol Rev Date: 2015-11-25 Impact factor: 11.056

3. The SARP Family Regulator Txn9 and Two-Component Response Regulator Txn11 are Key Activators for Trioxacarcin Biosynthesis in Streptomyces bottropensis.

Authors: Kui Yang; Li-Hua Qi; Mei Zhang; Xian-Feng Hou; Hai-Xue Pan; Gong-Li Tang; Wei Wang; Hua Yuan
Journal: Curr Microbiol Date: 2015-07-16 Impact factor: 2.188

Review 4. A comprehensive review of glycosylated bacterial natural products.

Authors: Sherif I Elshahawi; Khaled A Shaaban; Madan K Kharel; Jon S Thorson
Journal: Chem Soc Rev Date: 2015-11-07 Impact factor: 54.564

5. A multiply convergent platform for the synthesis of trioxacarcins.

Authors: Jakub Švenda; Nicholas Hill; Andrew G Myers
Journal: Proc Natl Acad Sci U S A Date: 2011-01-18 Impact factor: 11.205

6. Great diversity of KSα sequences from bat-associated microbiota suggests novel sources of uncharacterized natural products.

Authors: Paris S Salazar-Hamm; Jennifer J Marshall Hathaway; Ara S Winter; Nicole A Caimi; Debbie C Buecher; Ernest W Valdez; Diana E Northup
Journal: FEMS Microbes Date: 2022-04-18

Trioxacarcins, novel antitumor antibiotics. I. Producing organism, fermentation and biological activities.

1. Diastereoselective additions of allylmetal reagents to free and protected syn-α,β-dihydroxyketones enable efficient synthetic routes to methyl trioxacarcinoside A.

Review 2. Taxonomy, Physiology, and Natural Products of Actinobacteria.

3. The SARP Family Regulator Txn9 and Two-Component Response Regulator Txn11 are Key Activators for Trioxacarcin Biosynthesis in Streptomyces bottropensis.

Review 4. A comprehensive review of glycosylated bacterial natural products.

5. A multiply convergent platform for the synthesis of trioxacarcins.

6. Great diversity of KSα sequences from bat-associated microbiota suggests novel sources of uncharacterized natural products.

7. Resistance-Guided Mining of Bacterial Genotoxins Defines a Family of DNA Glycosylases.

8. Component-based syntheses of trioxacarcin A, DC-45-A1 and structural analogues.

9. Formation of gutingimycin: analytical investigation of trioxacarcin A-mediated alkylation of dsDNA.

10. Crystal structure of trioxacarcin A covalently bound to DNA.