Literature DB >> 6894691

Cardiovascular abnormalities in progeria. Case report and review of the literature.

P B Baker, N Baba, C P Boesel.   

Abstract

The cardiovascular findings in cases of progeria are similar in many respects to the changes associated with aging. These changes include prominent atherosclerosis and calcification of the aortic and mitral valves, coronary arteries, and aorta. The coronary artery disease leads to ischemic changes in the myocardium, including well-defined infarcts. In addition, the present case demonstrates narrowing of the small intramural arteries, which may have contributed to myocardial fibrosis.

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Year:  1981        PMID: 6894691

Source DB:  PubMed          Journal:  Arch Pathol Lab Med        ISSN: 0003-9985            Impact factor:   5.534


  25 in total

1.  Correction of cellular phenotypes of Hutchinson-Gilford Progeria cells by RNA interference.

Authors:  Shurong Huang; Lishan Chen; Nataliya Libina; Joel Janes; George M Martin; Judith Campisi; Junko Oshima
Journal:  Hum Genet       Date:  2005-10-06       Impact factor: 4.132

2.  New vascular insights into premature aging.

Authors:  Charles J Lowenstein; J Allen Bennett
Journal:  J Clin Invest       Date:  2018-12-18       Impact factor: 14.808

3.  Cardiac Abnormalities in Patients With Hutchinson-Gilford Progeria Syndrome.

Authors:  Ashwin Prakash; Leslie B Gordon; Monica E Kleinman; Ellen B Gurary; Joseph Massaro; Ralph D'Agostino; Mark W Kieran; Marie Gerhard-Herman; Leslie Smoot
Journal:  JAMA Cardiol       Date:  2018-04-01       Impact factor: 14.676

4.  Expression of the Hutchinson-Gilford progeria mutation during osteoblast development results in loss of osteocytes, irregular mineralization, and poor biomechanical properties.

Authors:  Eva Schmidt; Ola Nilsson; Antti Koskela; Juha Tuukkanen; Claes Ohlsson; Björn Rozell; Maria Eriksson
Journal:  J Biol Chem       Date:  2012-08-14       Impact factor: 5.157

5.  Aortic calcification in a patient with hutchinson-gilford progeria syndrome.

Authors:  Mehrdad Salamat; Pradip K Dhar; Daniela L Neagu; Jane B Lyon
Journal:  Pediatr Cardiol       Date:  2010-04-17       Impact factor: 1.655

6.  Progressive vascular smooth muscle cell defects in a mouse model of Hutchinson-Gilford progeria syndrome.

Authors:  Renee Varga; Maria Eriksson; Michael R Erdos; Michelle Olive; Ingrid Harten; Frank Kolodgie; Brian C Capell; Jun Cheng; Dina Faddah; Stacie Perkins; Hedwig Avallone; Hong San; Xuan Qu; Santhi Ganesh; Leslie B Gordon; Renu Virmani; Thomas N Wight; Elizabeth G Nabel; Francis S Collins
Journal:  Proc Natl Acad Sci U S A       Date:  2006-02-21       Impact factor: 11.205

7.  Increased mechanosensitivity and nuclear stiffness in Hutchinson-Gilford progeria cells: effects of farnesyltransferase inhibitors.

Authors:  Valerie L R M Verstraeten; Julie Y Ji; Kiersten S Cummings; Richard T Lee; Jan Lammerding
Journal:  Aging Cell       Date:  2008-03-10       Impact factor: 9.304

8.  Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome.

Authors:  Robert D Goldman; Dale K Shumaker; Michael R Erdos; Maria Eriksson; Anne E Goldman; Leslie B Gordon; Yosef Gruenbaum; Satya Khuon; Melissa Mendez; Renée Varga; Francis S Collins
Journal:  Proc Natl Acad Sci U S A       Date:  2004-06-07       Impact factor: 11.205

9.  A lamin A protein isoform overexpressed in Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and normal cells.

Authors:  Kan Cao; Brian C Capell; Michael R Erdos; Karima Djabali; Francis S Collins
Journal:  Proc Natl Acad Sci U S A       Date:  2007-03-14       Impact factor: 11.205

Review 10.  Mechanics of the nucleus.

Authors:  Jan Lammerding
Journal:  Compr Physiol       Date:  2011-04       Impact factor: 9.090

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