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Literature DB >> 6894124

Tuftsin and D-Arg3-tuftsin possess analgesic action.

Z S Herman, Z Stachura, L Opiełka, I Z Siemion, E Nawrocka.

Abstract

Tuftsin has marked analgesic activity but is less potent than D-Arg3-tuftsin. The absence of an antagonistic effect of naloxone on tuftsin and its analogue suggests that these substances do not act on opiate receptors. Tuftsin and its analogues may represent a new class of substances of interest in the search for new analgesics.

Entities: Chemical

Mesh：

Substances：

Year: 1981 PMID： 6894124 DOI： 10.1007/bf01965580

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

7 in total

1. Quantification of the analgesic activity of narcotic antagonists by a modified hot-plate procedure.

Authors: J P O'Callaghan; S G Holtzman
Journal: J Pharmacol Exp Ther Date: 1975-03 Impact factor: 4.030

2. Neurohypophyseal hormones and behavior: effects of intracerebroventricularly injected hormone analogs in mice.

Authors: R L Delanoy; A J Dunn; R Walter
Journal: Life Sci Date: 1979-02-12 Impact factor: 5.037

3. The characteristics, isolation and synthesis of the phagocytosis stimulating peptide tuftsin.

Authors: K Nishioka; A Constantopoulos; P S Satoh; V A Najjar
Journal: Biochem Biophys Res Commun Date: 1972-04-14 Impact factor: 3.575

4. A new phagocytosis-stimulating tetrapeptide hormone, tuftsin, and its role in disease.

Authors: V A Najjar; A Constantopoulos
Journal: J Reticuloendothel Soc Date: 1972-08

5. The effects of noradrenaline on rat's behaviour.

Authors: Z S Herman
Journal: Psychopharmacologia Date: 1970

6. Partial sequences of histones with tuftsin activity.

Authors: D Konopínska; E Nawrocka; I Z Siemion; S Slopek; S Szymaniec; E Klonowska
Journal: Int J Pept Protein Res Date: 1977-01

7. "Tuftsin": a natural phagocytosis stimulating peptide.

Authors: V A Najjar; K Nishioka
Journal: Nature Date: 1970-11-14 Impact factor: 49.962

7 in total

6 in total

Tuftsin and D-Arg3-tuftsin possess analgesic action.

1. Quantification of the analgesic activity of narcotic antagonists by a modified hot-plate procedure.

2. Neurohypophyseal hormones and behavior: effects of intracerebroventricularly injected hormone analogs in mice.

3. The characteristics, isolation and synthesis of the phagocytosis stimulating peptide tuftsin.

4. A new phagocytosis-stimulating tetrapeptide hormone, tuftsin, and its role in disease.

5. The effects of noradrenaline on rat's behaviour.

6. Partial sequences of histones with tuftsin activity.

7. "Tuftsin": a natural phagocytosis stimulating peptide.

Review 1. Cytophilic gamma-globulin and tuftsin.

Review 2. Tuftsin analogs and their biological activity.

3. L-prolyl-L-arginine fragment of tuftsin peptide chain elicits analgesic action.

4. The Analgesic Activity of Bestatin as a Potent APN Inhibitor.

5. Tuftsin promotes an anti-inflammatory switch and attenuates symptoms in experimental autoimmune encephalomyelitis.

6. Synthesis and antimicrobial activity of amino acid and peptide derivatives of mycophenolic acid.