Literature DB >> 6894091

Effect of 1,25-dihydroxycholecalciferol and 1,25-dihydroxycholecalciferol glycoside on 2,3-diphosphoglycerate levels of the rat erythrocyte.

M I Skliar, M C Fernandez, H Faienza, M B Orsatti, R C Puche, R L Boland, M I Skliar.   

Abstract

The erythrocytes of rats treated with 1, 25-dihydroxycholecalciferol or 1, 25-dihydroxycholecalciferol glycoside showed decreased levels of 2, 3-diphosphoglycerate. The same result has been obtained in vitro, indicating a direct effect of the sterol on the red cell. The glycoside is less active than the free sterol in vivo and more active in vitro. The decreased levels of diphosphoglycerate induced tissue hypoxia as shown by a higher plasma lactate/pyruvate ratio and a three fold increase in plasma erythropoietin concentration.

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Year:  1980        PMID： 6894091     DOI： 10.1007/bf00587932

Source DB:  PubMed          Journal:  Pflugers Arch        ISSN： 0031-6768            Impact factor:   3.657


  16 in total

1.  Bio-assay of erythropoietin in mice made polycythaemic by exposure to air at a reduced pressure.

Authors:  P M COTES; D R BANGHAM
Journal:  Nature       Date:  1961-09-09       Impact factor: 49.962

2.  1, 25-dihydroxyvitamin D3-glycoside: identification of a calcinogenic principle of Solanium malocoxylon.

Authors:  M R Haussler; R H Wasserman; T A McCain; M Peterlik; K M Bursac; M R Hughes
Journal:  Life Sci       Date:  1976-05-15       Impact factor: 5.037

3.  2,3-diphosphoglycerate phosphatase from human erythrocytes. General properties and activation by anions.

Authors:  Z B Rose; J Liebowitz
Journal:  J Biol Chem       Date:  1970-06       Impact factor: 5.157

4.  Effects of Solanum malacoxylon on embryonic bone in vitro and on isolated mitochondria.

Authors:  R C Puche; M E Locatto
Journal:  Calcif Tissue Res       Date:  1974

5.  Impaired oxygen release caused by alterations of the metabolism in the erythrocytes in diabetes.

Authors:  J Ditzel
Journal:  Lancet       Date:  1972-04-01       Impact factor: 79.321

6.  Effect of Solanum malocoxylon on the serum levels of calcium and phosphate in thyroparathyroidectomized and rachitic rats.

Authors:  C Campos; M Ladizesky; C Mautalen
Journal:  Calcif Tissue Res       Date:  1973-10-23

7.  Further experiences with assays, units, and standards of erythropoietin.

Authors:  G Keighley
Journal:  Ann N Y Acad Sci       Date:  1968-03-29       Impact factor: 5.691

8.  A salt mixture supplying the national research council estimates of the mineral requirements of the rat.

Authors:  F W Bernhart; R M Tomarelli
Journal:  J Nutr       Date:  1966-08       Impact factor: 4.798

9.  Effects of 1alpha,25-dihydroxyvitamin D3 and Solanum glaucophyllum on intestinal calcium and phosphate transport and on plasma Ca, Mg and P levels in the rat.

Authors:  M W Walling; D V Kimberg
Journal:  Endocrinology       Date:  1975-12       Impact factor: 4.736

10.  Mechanism of action of thyroid hormones on erythrocyte 2,3-diphosphoglyceric acid synthesis.

Authors:  L M Snyder; W J Reddy
Journal:  J Clin Invest       Date:  1970-11       Impact factor: 14.808
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  3 in total

1.  Erythropoietin attenuates neurological and histological consequences of toxic demyelination in mice.

Authors:  Nora Hagemeyer; Susann Boretius; Christoph Ott; Axel Von Streitberg; Henrike Welpinghus; Swetlana Sperling; Jens Frahm; Mikael Simons; Pietro Ghezzi; Hannelore Ehrenreich
Journal:  Mol Med       Date:  2012-05-09       Impact factor: 6.354

2.  Respiratory alkalosis and reduced plasmatic concentration of ionized calcium in rats treated with 1,25 dihydroxycholecalciferol.

Authors:  M E Locatto; M C Fernandez; D A Caferra; M C Gimenez; M C Vidal; R C Puche
Journal:  Calcif Tissue Int       Date:  1984-09       Impact factor: 4.333

3.  The effect of 1 alpha, 25-dihydroxycholecalciferol on iron metabolism.

Authors:  A S Dusso; R C Puche
Journal:  Blut       Date:  1985-08
  3 in total

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