| Literature DB >> 6894019 |
R A Kark, M M Budelli, D M Becker, L P Weiner, A B Forsythe.
Abstract
The activity of lipoamide dehydrogenase was abnormally heat-labile in homogenized platelets from seven patients with as recessive ataxia conforming to the syndrome of Friedreich ataxia or clinical variants. Taken together, the abnormality and previous findings of low activity and abnormal kinetic properties are compatible with a change in the conformation of the enzyme in these patients.Entities:
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Year: 1981 PMID： 6894019 DOI： 10.1212/wnl.31.2.199
Source DB: PubMed Journal: Neurology ISSN： 0028-3878 Impact factor: 9.910