Literature DB >> 6893648

Thyroid-stimulating immunoglobulins in neonatal Graves's disease.

C S Teng, T C Tong, J H Hutchison, R T Yeung.   

Abstract

Two patients with neonatal Graves's disease are reported. One of them had a delayed onset because of suppression of the fetal thyroid gland by antithyroid drug taken by the mother during pregnancy. Thyroid-stimulating immunoglobulins (TSAb), measured by a receptor assay, were present in both babies when they were thyrotoxic, and also in their mothers. TSAb were undetectable in both babies 1 year after birth. This strongly supports a pathogenetic role of TSAb in this condition through transplacental transfer of maternal TSAb.

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Year:  1980        PMID： 6893648      PMCID： PMC1626952          DOI： 10.1136/adc.55.11.894

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN： 0003-9888            Impact factor:   3.791


  5 in total

1.  Thyroid-stimulating immunoglobulins in Graves' disease.

Authors:  B R Smith; R Hall
Journal:  Lancet       Date:  1974-08-24       Impact factor: 79.321

2.  Changes in thyroid-stimulating antibody activity in Graves' disease treated with antithyroid drug and its relationship to relapse: a prospective study.

Authors:  C S Teng; R T Yeung
Journal:  J Clin Endocrinol Metab       Date:  1980-01       Impact factor: 5.958

3.  Placental transmission of thyroid-stimulating immunoglobulins.

Authors:  S M Dirmikis; D S Munro
Journal:  Br Med J       Date:  1975-06-21

4.  Neonatal thyrotoxicosis is associated with transplacental passage of human thyroid stimulating immunoglobulin (HTSI).

Authors:  I Mitchell; G Shenfield; J Brash
Journal:  Arch Dis Child       Date:  1976-07       Impact factor: 3.791

5.  Relation of thyroid-stimulating immunoglobulins to thyroid function and effects of surgery, radioiodine, and antithyroid drugs.

Authors:  E D Mukhtar; B R Smith; G A Pyle; R Hall; P Vice
Journal:  Lancet       Date:  1975-03-29       Impact factor: 79.321
  5 in total
  2 in total

1.  Clinical applications of assays for thyrotropin-receptor antibodies in Graves' disease.

Authors:  J Ginsberg; C von Westarp
Journal:  CMAJ       Date:  1986-05-15       Impact factor: 8.262

2.  Transient neonatal hyperthyroidism and maternal thyroid stimulating immunoglobulins.

Authors:  T Matsuda; T Momoi; K Akaishi; T Yagura; K Kasagi; K Endo
Journal:  Arch Dis Child       Date:  1988-02       Impact factor: 3.791
  2 in total

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