Management of Thygeson's superficial punctate keratitis.

Four patients had Thygeson's superficial punctate keratitis of one to 16 years' duration. One patient was completely unresponsive to topical corticosteroids, and the remaining three patients had only partial resolution of signs or symptoms while using topical corticosteroids. In all cases, rapid resolution of the epithelial lesions occurred with symptomatic relief after patching for 24 hours or after the use of therapeutic soft contact lenses. Three of the four patients have tolerated daily or extended wear of soft contact lenses accompanied by relief of both signs and symptoms. The use of therapeutic soft contact lenses may provide an alternative to topical corticosteroids in the treatment of Thygeson's superficial punctate keratitis.