Literature DB >> 6891904

Anticarcinogenic actions of water-soluble and alcohol-insoluble fractions from culture medium of Lentinus edodes mycelia.

N Sugano, Y Hibino, Y Choji, H Maeda.   

Abstract

The water-soluble (LEM) and alcohol-insoluble (LAP and LAP1) fractions were prepared from the culture medium of Lentinus edodes mycelia which was composed of bagasse and rice bran. LEM suppressed rat hepatocarcinogenesis and its cell proliferation of rat-ascites hepatoma to about 50% or less of each control group. LAP also suppressed cell proliferation at almost the same rate. LAP1 induced many small cells in the ascites and significantly raised the survival rate of hepatoma-bearing rats. Thus, anticarcinogenic action was revealed in LAP or LAP1 fractions which were mainly composed of xylose-containing polysaccharide and protein.

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Year:  1982        PMID： 6891904     DOI： 10.1016/0304-3835(82)90022-2

Source DB:  PubMed          Journal:  Cancer Lett        ISSN： 0304-3835            Impact factor:   8.679


  7 in total

1.  Protection of liver cells against experimental damage by extract of cultured Lentinus edodes mycelia (LEM).

Authors:  Y Mizoguchi; H Katoh; K Kobayashi; S Yamamoto; S Morisawa
Journal:  Gastroenterol Jpn       Date:  1987-08

2.  Effects of extract of cultured Lentinus edodes mycelia (LEM) on polyclonal antibody response induced by pokeweed mitogen.

Authors:  Y Mizoguchi; H Katoh; K Kobayashi; S Yamamoto; S Morisawa
Journal:  Gastroenterol Jpn       Date:  1987-10

3.  Structural analysis of glycogen-like polysaccharides having macrophage-activating activity in extracts of Lentinula edodes mycelia.

Authors:  Hiroaki Kojima; Junji Akaki; Satomi Nakajima; Kaeko Kamei; Makoto Tamesada
Journal:  J Nat Med       Date:  2009-08-27       Impact factor: 2.343

4.  Inhibition (in vitro) of replication and of the cytopathic effect of human immunodeficiency virus by an extract of the culture medium of Lentinus edodes mycelia.

Authors:  T S Tochikura; H Nakashima; Y Ohashi; N Yamamoto
Journal:  Med Microbiol Immunol       Date:  1988       Impact factor: 3.402

5.  Lentinula edodes mycelia extract plus adjuvant chemotherapy for breast cancer patients: Results of a randomized study on host quality of life and immune function improvement.

Authors:  Yukiko Nagashima; Shigehumi Yoshino; Shigeru Yamamoto; Noriko Maeda; Tatsuya Azumi; Yoshifumi Komoike; Kiyotaka Okuno; Tsutomu Iwasa; Junji Tsurutani; Kazuhiko Nakagawa; Oka Masaaki; Nagano Hiroaki
Journal:  Mol Clin Oncol       Date:  2017-07-25

6.  Evaluation of host quality of life and immune function in breast cancer patients treated with combination of adjuvant chemotherapy and oral administration of Lentinula edodes mycelia extract.

Authors:  Yukiko Nagashima; Noriko Maeda; Shigeru Yamamoto; Shigefumi Yoshino; Masaaki Oka
Journal:  Onco Targets Ther       Date:  2013-07-09       Impact factor: 4.147

7.  An in vivo study of hepatic and splenic interleukin-1 beta mRNA expression following oral PSK or LEM administration.

Authors:  H Morinaga; K Tazawa; H Tagoh; A Muraguchi; M Fujimaki
Journal:  Jpn J Cancer Res       Date:  1994-12
  7 in total

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