Literature DB >> 6889804

Carcinoma in situ of the testis. Some ultrastructural characteristics of germ cells.

R Albrechtsen, M H Nielsen, N E Skakkebaek, U Wewer.   

Abstract

The two cytoplasmic organelles, dense-cored vesicles and "nuages" have been considered to allow positive identification of primordial germ cells in rodents, but no use of these potential markers has been applied to human material. We have observed dense-cored vesicles and "nuages" in the abnormal germ cells of carcinoma in situ of the testis and thus brought further evidence for the germ cell origin of this lesion. These organelles may be useful cytoplasmic markers in the study of germ cell tumors.

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Year:  1982        PMID： 6889804     DOI： 10.1111/j.1699-0463.1982.tb00097_90a.x

Source DB:  PubMed          Journal:  Acta Pathol Microbiol Immunol Scand A        ISSN： 0108-0164


  7 in total

Review 1.  Carcinoma in situ in testicular biopsies.

Authors:  K Mazanec; I Vorechovsky
Journal:  Int Urol Nephrol       Date:  1989       Impact factor: 2.370

2.  Atypical germ cells of the testis. Comparative ultrastructural and immunohistochemical investigations.

Authors:  C Sigg; C Hedinger
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1984

3.  Intermitochondrial cement (nuage) in a spermatocytic seminoma: comparison with classical seminoma and normal testis.

Authors:  Manrico Morroni; Angela Maria Cangiotti; Daniela Marzioni; Antonella D'Angelo; Rosaria Gesuita; Michele De Nictolis
Journal:  Virchows Arch       Date:  2008-04-19       Impact factor: 4.064

4.  Carcinoma in situ testis displays permissive chromatin modifications similar to immature foetal germ cells.

Authors:  K Almstrup; J E Nielsen; O Mlynarska; M T Jansen; A Jørgensen; N E Skakkebæk; E Rajpert-De Meyts
Journal:  Br J Cancer       Date:  2010-09-07       Impact factor: 7.640

5.  Genome-wide gene expression profiling of testicular carcinoma in situ progression into overt tumours.

Authors:  K Almstrup; C E Hoei-Hansen; J E Nielsen; U Wirkner; W Ansorge; N E Skakkebaek; E Rajpert-De Meyts; H Leffers
Journal:  Br J Cancer       Date:  2005-05-23       Impact factor: 7.640

6.  miR-379 deletion ameliorates features of diabetic kidney disease by enhancing adaptive mitophagy via FIS1.

Authors:  Mitsuo Kato; Maryam Abdollahi; Ragadeepthi Tunduguru; Walter Tsark; Zhuo Chen; Xiwei Wu; Jinhui Wang; Zhen Bouman Chen; Feng-Mao Lin; Linda Lanting; Mei Wang; Janice Huss; Patrick T Fueger; David Chan; Rama Natarajan
Journal:  Commun Biol       Date:  2021-01-04

7.  Evidence that active demethylation mechanisms maintain the genome of carcinoma in situ cells hypomethylated in the adult testis.

Authors:  D G Kristensen; J E Nielsen; A Jørgensen; N E Skakkebæk; E Rajpert-De Meyts; K Almstrup
Journal:  Br J Cancer       Date:  2013-11-28       Impact factor: 7.640
  7 in total

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