Literature DB >> 6889583

Synthesis and pharmacological activity of dermorphin and its N-terminal sequences.

S Salvadori, G Sarto, R Tomatis.   

Abstract

H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2 (demorphin), and opiate-like peptide, and tri-, tetra-, penta- and hexapeptide-amide analogs, were synthesized by conventional methods in solution, to determine the minimum peptide chain-length, required for analgesic activity.

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Year:  1982        PMID: 6889583     DOI: 10.1111/j.1399-3011.1982.tb02639.x

Source DB:  PubMed          Journal:  Int J Pept Protein Res        ISSN: 0367-8377


  5 in total

1.  Antinociception and physical dependence produced by [D-Arg2] dermorphin tetrapeptide analogues and morphine in rats.

Authors:  K Chaki; S Kawamura; K Kisara; S Sakurada; T Sakurada; Y Sasaki; T Sato; K Susuki
Journal:  Br J Pharmacol       Date:  1988-09       Impact factor: 8.739

2.  A conformational study of the opioid peptide dermorphin by one-dimensional and two-dimensional nuclear magnetic resonance spectroscopy.

Authors:  A Pastore; P A Temussi; S Salvadori; R Tomatis; P Mascagni
Journal:  Biophys J       Date:  1985-08       Impact factor: 4.033

3.  Involvement of mu-opioid receptors in the modulation of pituitary-adrenal axis in normal and stressed rats.

Authors:  E C degli Uberti; F Petraglia; M Bondanelli; A L Guo; A Valentini; S Salvadori; M Criscuolo; R E Nappi; A R Genazzani
Journal:  J Endocrinol Invest       Date:  1995-01       Impact factor: 4.256

4.  Dermorphin, a new opioid peptide, stimulates thyrotropin secretion in normal subjects.

Authors:  E Roti; E Degli Uberti; S Salvadori; M Bianconi; R Emanuele; C Rotola; G Trasforini; G Robuschi; R Tomatis; A Gnudi
Journal:  J Endocrinol Invest       Date:  1984-06       Impact factor: 4.256

Review 5.  Rediscovery of old drugs: the forgotten case of dermorphin for postoperative pain and palliation.

Authors:  Jan M Keppel Hesselink; Michael E Schatman
Journal:  J Pain Res       Date:  2018-11-23       Impact factor: 3.133

  5 in total

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