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Literature DB >> 6888656

A central mechanism of action for taurine: osmoregulation, bivalent cations, and excitation threshold.

Abstract

A postulated zinc-taurine complex, with a zinc affinity intermediate between that for glutamic acid dehydrogenase and the calcium binding protein(s), provides an explanation for a series of seemingly unrelated biochemical and physiological effects of taurine. The proposed complex suggests a central mechanism for the action of taurine, such as a bicarbonate and pH dependent influence on calcium and zinc movements (and vice versa), the osmoregulatory role of taurine, and its effect on the excitation threshold.

Entities: Chemical

Mesh：

Substances：

Year: 1983 PMID： 6888656 DOI： 10.1007/bf00964706

Source DB: PubMed Journal: Neurochem Res ISSN： 0364-3190 Impact factor: 3.996

26 in total

Review 1. The neuropharmacology of taurine.

Authors: A Barbeau; N Inoue; Y Tsukada; R F Butterworth
Journal: Life Sci Date: 1975-09-01 Impact factor: 5.037

2. The distribution of taurine, gamma-aminobutyric acid and inorganic ions between plasma and erythrocytes in flounder (Platichthys flesus) at different plasma osmolalities.

Authors: K Fugelli; K E Zachariassen
Journal: Comp Biochem Physiol A Comp Physiol Date: 1976

3. Amino acid transport into the cerebrospinal fluid of the rat.

Authors: G M Franklin; D S Dudzinski; R W Cutler
Journal: J Neurochem Date: 1975-02 Impact factor: 5.372

4. Taurine, cysteinesulfinic acid decarboxylase and glutamic acid in brain.

Authors: D K Rassin
Journal: Adv Exp Med Biol Date: 1981 Impact factor: 2.622

5. Taurine nutrition in man.

Authors: G E Gaull
Journal: Adv Exp Med Biol Date: 1981 Impact factor: 2.622

6. Histochemical localization of carbonic anhydrase in vertebrate nervous tissue.

Authors: V Parthe
Journal: J Neurosci Res Date: 1981 Impact factor: 4.164

7. Na+-dependent uptake and release of taurine by neuroblastoma x glioma hybrid cells.

Authors: K Kürzinger; B Hamprecht
Journal: J Neurochem Date: 1981-10 Impact factor: 5.372

8. How are tissue taurine concentrations regulated?

Authors:
Journal: Adv Exp Med Biol Date: 1981 Impact factor: 2.622

9. Taurine: a role in osmotic regulation of mammalian brain and possible clinical significance.

Authors: J H Thurston; R E Hauhart; J A Dirgo
Journal: Life Sci Date: 1980-05-12 Impact factor: 5.037

10. Induction by hydrocortisone of glutamine synthetase in mouse primary astrocyte cultures.

Authors: B H Juurlink; A Schousboe; O S Jørgensen; L Hertz
Journal: J Neurochem Date: 1981-01 Impact factor: 5.372

13 in total

1. Nico M. van Gelder, the inquisitive neurochemist.

Authors: A Hamberger; T A Reader
Journal: Neurochem Res Date: 1999-11 Impact factor: 3.996

2. Taurine and zinc modulate outgrowth from goldfish retinal explants.

Authors: S Nusetti; F Obregón; M Quintal; Z Benzo; L Lima
Journal: Neurochem Res Date: 2005-12 Impact factor: 3.996

Review 3. Anticonvulsant drug action and regional neurotransmitter amino acid changes.

Authors: A G Chapman; G P Hart
Journal: J Neural Transm Date: 1988 Impact factor: 3.575

4. Effects of taurine on cell morphology and expression of low-affinity GABA receptors in cultured cerebellar granule cells.

Authors: J H Abraham; A Schousboe
Journal: Neurochem Res Date: 1989-10 Impact factor: 3.996

5. Brain taurine content as a function of cerebral metabolic rate: osmotic regulation of glucose derived water production.

Authors: N M van Gelder
Journal: Neurochem Res Date: 1989-06 Impact factor: 3.996