Literature DB >> 6884784

Intraocular-pressure-lowering effect of low-dosage combination of guanethidine and terbutaline in rabbit.

L Bonomi, S Perfetti, R Bellucci, F Massa, G C Gamba.   

Abstract

A low dosage combination of terbutaline plus guanethidine was applied topically to the eyes of rabbits with experimentally induced ocular hypertension, markedly lowering intraocular pressure. The effect of this combination is markedly greater than that produced separately by the two components at corresponding dosages and seems to be due to a true synergistic phenomenon. The low-dosage combination of terbutaline and guanethidine appears to be well tolerated, very potent and effective as a topical ocular hypotensive agent.

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Year:  1983        PMID： 6884784     DOI： 10.1007/bf02186669

Source DB:  PubMed          Journal:  Graefes Arch Clin Exp Ophthalmol        ISSN： 0721-832X            Impact factor:   3.117


  9 in total

1.  Effect of beta-adrenergic agonists and antagonists on repeated tonometry and episcleral venous pressure.

Authors:  K Wettrell; K Wilke; M Pandolfi
Journal:  Exp Eye Res       Date:  1977-06       Impact factor: 3.467

2.  [ON THE ACTION OF ALEUDRIN ON THE NORMAL HUMAN EYE].

Authors:  L BONOMI
Journal:  Boll Ocul       Date:  1964-06

3.  An improved model of experimentally induced ocular hypertension in the rabbit.

Authors:  L Bonomi; L Tomazzoli; D Jaria
Journal:  Invest Ophthalmol       Date:  1976-09

4.  Comparison of the effects of nine beta-adrenergic blocking agents on intraocular pressure in rabbits.

Authors:  L Bonomi; S Perfetti; E Noya; R Bellucci; F Massa
Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol       Date:  1979-03-05

5.  Adrenergic drugs and intraocular pressure: effects of selective beta-adrenergic agonists.

Authors:  D E Potter; J M Rowland
Journal:  Exp Eye Res       Date:  1978-12       Impact factor: 3.467

6.  Guanethidine and adrenaline used in combination in chronic simple glaucoma.

Authors:  J A Roth
Journal:  Br J Ophthalmol       Date:  1973-07       Impact factor: 4.638

7.  Epinephrine dose-response characteristics of glaucomatous human eyes following chemical sympathectomy with 6-Hydroxydopamine.

Authors:  M G Holland; C P Wei
Journal:  Ann Ophthalmol       Date:  1973-06

8.  Pharmacology of ocular drugs: 2. Epinephrine.

Authors:  S M Podos
Journal:  Ophthalmology       Date:  1980-07       Impact factor: 12.079

9.  Treatment of chronic simple glaucoma with an adrenaline/guanethidine combination at three different dosages (comparative double-blind study).

Authors:  U Urner-Bloch; J E Aeschlimann; B P Gloor
Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol       Date:  1980
  9 in total

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