Literature DB >> 6884518

The phorbol ester TPA increases the affinity of exocytosis for calcium in 'leaky' adrenal medullary cells.

D E Knight, P F Baker.   

Abstract

Exposure of 'leaky' bovine adrenal medullary cells to the phorbol ester TPA causes a shift in the calcium-activation curve to lower calcium concentrations without altering the levels of secretion at the extremes of the activation curve. These results are consistent with a role for protein kinase C in exocytosis.

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Year:  1983        PMID： 6884518     DOI： 10.1016/0014-5793(83)80944-2

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  50 in total

Review 1.  The regulation of neurotransmitter secretion by protein kinase C.

Authors:  P F Vaughan; J H Walker; C Peers
Journal:  Mol Neurobiol       Date:  1998-10       Impact factor: 5.590

2.  Exocytosis from permeabilized bovine adrenal chromaffin cells is differently modulated by guanosine 5'-[gamma-thio]triphosphate and guanosine 5'-[beta gamma-imido]triphosphate. Evidence for the involvement of various guanine nucleotide-binding proteins.

Authors:  G Ahnert-Hilger; U Wegenhorst; B Stecher; K Spicher; W Rosenthal; M Gratz
Journal:  Biochem J       Date:  1992-06-01       Impact factor: 3.857

3.  Mechanism of hepatic glycogen synthase inactivation induced by Ca2+-mobilizing hormones. Studies using phospholipase C and phorbol myristate acetate.

Authors:  P F Blackmore; W G Strickland; S B Bocckino; J H Exton
Journal:  Biochem J       Date:  1986-07-01       Impact factor: 3.857

4.  Regulation of protein phosphorylation in pancreatic acini. Distinct effects of Ca2+ ionophore A23187 and 12-O-tetradecanoylphorbol 13-acetate.

Authors:  D B Burnham; P Munowitz; S R Hootman; J A Williams
Journal:  Biochem J       Date:  1986-04-01       Impact factor: 3.857

5.  Habituation in the single cell: diminished secretion of norepinephrine with repetitive depolarization of PC12 cells.

Authors:  P N McFadden; D E Koshland
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6.  Differential requirements for Ca2+ concentrations for catecholamine release and biosynthesis in isolated bovine adrenal chromaffin cells.

Authors:  H Houchi; M Yoshizumi; Y Ishimura; M Oka
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1996-04       Impact factor: 3.000

Review 7.  Molecular mechanisms of exocytosis: the adrenal chromaffin cell as a model system.

Authors:  W J Strittmatter
Journal:  Cell Mol Neurobiol       Date:  1988-03       Impact factor: 5.046

Review 8.  Membrane fusion.

Authors:  K N Burger; A J Verkleij
Journal:  Experientia       Date:  1990-06-15

9.  Phorbol ester, an activator of protein kinase C, enhances calcium-dependent release of sympathetic neurotransmitter.

Authors:  A R Wakade; R K Malhotra; T D Wakade
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1985-10       Impact factor: 3.000

10.  Protein kinase C and clostridial neurotoxins affect discrete and related steps in the secretory pathway.

Authors:  M A Bittner; R W Holz
Journal:  Cell Mol Neurobiol       Date:  1993-12       Impact factor: 5.046
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