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Literature DB >> 6884491

Lead distribution in the nervous system of 8-month-old rats intoxicated since birth by lead.

J M Lefauconnier, G Bernard, F Mellerio, A Sebille, E Cesarini.

Abstract

Lead levels in the nervous system of rats intoxicated for 8 months by lead acetate (0.2% in drinking water) varied according to the region: the lowest levels were observed in sciatic nerve and the highest in hippocampus and cerebral neocortex, while intermediate levels were observed in pons medulla, cerebellum, midbrain, hypothalamus and striatum.

Entities: Chemical Disease Species

Mesh：

Substances：
Lead

Year: 1983 PMID： 6884491 DOI： 10.1007/bf01989787

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

14 in total

1. ACUTE LEAD ENCEPHALOPATHY OF CHILDHOOD. HISTOLOGIC AND CHEMICAL STUDIES, WITH PARTICULAR REFERENCE TO ANGIOPATHIC ASPECTS.

Authors: H OKAZAKI; S M ARONSON; D DIMAIO; J E OLVERA
Journal: Trans Am Neurol Assoc Date: 1963

2. Hippocampus: selective concentration of lead in the normal rat brain.

Authors: E J Fjerdingstad; G Danscher; E Fjerdingstad
Journal: Brain Res Date: 1974-11-15 Impact factor: 3.252

3. The distribution of radioactive lead (210Pb) in the cerebellum of developing rats.

Authors: J A Thomas; F D Dallenbach; M Thomas
Journal: J Pathol Date: 1973-01 Impact factor: 7.996

4. Experimental oral lead toxicity in young dogs. Clinical and morphologic effects.

Authors: H D Stowe; R A Goyer; M Krigman; M Wilson; M Cates
Journal: Arch Pathol Date: 1973-02

5. Effects of inorganic lead on RNA, DNA and protein content in the developing neonatal rat brain.

Authors: I A Michaelson
Journal: Toxicol Appl Pharmacol Date: 1973-12 Impact factor: 4.219

6. Earthenware containers as a source of fatal lead poisoning.

Authors: M Klein; R Namer; E Harpur; R Corbin
Journal: N Engl J Med Date: 1970-09-24 Impact factor: 91.245

7. The pathogenesis of lead encephalopathy. Effects of lead carbonate feedings on morphology, lead content, and mitochondrial respiration in brains of immature and adult rats.

Authors: J S Hsu; M M Herman; H J Hsu; P Mortell
Journal: Virchows Arch A Pathol Anat Histol Date: 1980

Review 6. Transplacental transport of lead.

Authors: R A Goyer
Journal: Environ Health Perspect Date: 1990-11 Impact factor: 9.031

6 in total

Lead distribution in the nervous system of 8-month-old rats intoxicated since birth by lead.

1. ACUTE LEAD ENCEPHALOPATHY OF CHILDHOOD. HISTOLOGIC AND CHEMICAL STUDIES, WITH PARTICULAR REFERENCE TO ANGIOPATHIC ASPECTS.

2. Hippocampus: selective concentration of lead in the normal rat brain.

3. The distribution of radioactive lead (210Pb) in the cerebellum of developing rats.

4. Experimental oral lead toxicity in young dogs. Clinical and morphologic effects.

5. Effects of inorganic lead on RNA, DNA and protein content in the developing neonatal rat brain.

6. Earthenware containers as a source of fatal lead poisoning.

7. The pathogenesis of lead encephalopathy. Effects of lead carbonate feedings on morphology, lead content, and mitochondrial respiration in brains of immature and adult rats.

8. Lead in blood and brain regions of rats chronically exposed to low doses of the metal.

9. Regressive or lethal lead encephalopathy in the suckling rat. Correlation of lead levels and morphological findings.

10. Lead encephalopathy in neonatal Long-Evans rats: morphologic studies.

1. Lead-exposure of neonatal rats through maternal milk : A confounded model.

Review 2. Childhood Lead Exposure and Adult Neurodegenerative Disease.

Review 3. Environmental factors in the development and progression of late-onset Alzheimer's disease.

4. Lead dysregulates serine/threonine protein phosphatases in human neurons.

Review 5. Results of lead research: prenatal exposure and neurological consequences.

Review 6. Transplacental transport of lead.