Literature DB >> 6883353

Doxorubicin in pregnancy: possible transplacental passage.

G I Karp, P von Oeyen, F Valone, V K Khetarpal, M Israel, R J Mayer, F D Frigoletto, M B Garnick.   

Abstract

Two pregnant women with lymphoproliferative disorders were treated with doxorubicin-containing regimens. Both patients delivered shortly after a dose of doxorubicin. One child was healthy and the other was stillborn. Measurements of anthracycline levels in placental, cord, and fetal tissues by high-performance liquid chromatography suggest that doxorubicin may be transported across the placenta.

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Year:  1983        PMID： 6883353

Source DB:  PubMed          Journal:  Cancer Treat Rep        ISSN： 0361-5960


  12 in total

1.  Narrowing the embryologic window of the adriamycin-induced fetal rat model of esophageal atresia and tracheoesophageal fistula.

Authors:  B Qi; J A Diez-Pardo; C Navarro; J A Tovar
Journal:  Pediatr Surg Int       Date:  1996-08       Impact factor: 1.827

Review 2.  T cell non-Hodgkin's lymphoma presenting in the first trimester of pregnancy.

Authors:  C C Lees; M Tsirigotis; J V Carr; M A Richards
Journal:  Postgrad Med J       Date:  1994-05       Impact factor: 2.401

Review 3.  Clinical pharmacokinetics of doxorubicin.

Authors:  P A Speth; Q G van Hoesel; C Haanen
Journal:  Clin Pharmacokinet       Date:  1988-07       Impact factor: 6.447

Review 4.  Treating breast cancer during pregnancy. What can be taken safely?

Authors:  M Espié; C Cuvier
Journal:  Drug Saf       Date:  1998-02       Impact factor: 5.606

Review 5.  Transplacental Passage and Fetal Effects of Antineoplastic Treatment during Pregnancy.

Authors:  Silvia Triarico; Serena Rivetti; Michele Antonio Capozza; Alberto Romano; Palma Maurizi; Stefano Mastrangelo; Giorgio Attinà; Antonio Ruggiero
Journal:  Cancers (Basel)       Date:  2022-06-24       Impact factor: 6.575

Review 6.  Placental transfer of drugs administered to the mother.

Authors:  G M Pacifici; R Nottoli
Journal:  Clin Pharmacokinet       Date:  1995-03       Impact factor: 6.447

Review 7.  Pharmacokinetics of anticancer drugs in children.

Authors:  W R Crom; A M Glynn-Barnhart; J H Rodman; M E Teresi; R E Kavanagh; M L Christensen; M V Relling; W E Evans
Journal:  Clin Pharmacokinet       Date:  1987-03       Impact factor: 6.447

8.  Pharmacokinetics of doxorubicin in pregnant women.

Authors:  Rachel J Ryu; Sara Eyal; Henry G Kaplan; Arezoo Akbarzadeh; Karen Hays; Kristin Puhl; Thomas R Easterling; Stacey L Berg; Kathleen A Scorsone; Eric M Feldman; Jason G Umans; Menachem Miodovnik; Mary F Hebert
Journal:  Cancer Chemother Pharmacol       Date:  2014-02-15       Impact factor: 3.333

Review 9.  Investigation of 7-dehydrocholesterol reductase pathway to elucidate off-target prenatal effects of pharmaceuticals: a systematic review.

Authors:  M R Boland; N P Tatonetti
Journal:  Pharmacogenomics J       Date:  2016-07-12       Impact factor: 3.550

Review 10.  Cancer treatment in pregnant women.

Authors:  Pawel Basta; Anna Bak; Krzysztof Roszkowski
Journal:  Contemp Oncol (Pozn)       Date:  2014-10-18
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