| Literature DB >> 6881608 |
A Miadonna, A Tedeschi, E Leggieri, M Cottini, M Restuccia, C Bianchini.
Abstract
Specific degranulation of mast cells and basophils depends upon transmembrane calcium flow. In the present studies the protective effect of the calcium-antagonist drug verapamil against allergen-induced asthma was assessed in eight atopic patients. The results of this study showed that verapamil, administered both orally or by aerosol, can prevent the specific bronchoconstriction.Entities:
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Year: 1983 PMID： 6881608
Source DB: PubMed Journal: Ann Allergy ISSN： 0003-4738