Literature DB >> 6879184

Angiotensin synthesis in the brain and increased turnover in hypertensive rats.

D Ganten, K Hermann, C Bayer, T Unger, R E Lang.   

Abstract

The missing link in the evidence for an active endogenous renin angiotensin system in the brain has been the demonstration of local angiotensin synthesis in the central nervous system in vivo. In this report the extraction and characterization of angiotensin I and angiotensin II from the brain of rats is described. The accumulation of angiotensin I was enhanced in hypertensive rats when the conversion to angiotensin II was blocked in vivo by the converting enzyme inhibitor captopril.

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Year:  1983        PMID： 6879184     DOI： 10.1126/science.6879184

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  46 in total

1.  Angiotensin receptor II is present in dopaminergic cell line of rat substantia nigra and it is down regulated by aminochrome.

Authors:  A Dagnino-Subiabre; K Marcelain; C Arriagada; I Paris; P Caviedes; R Caviedes; J Segura-Aguilar
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2.  A view of renin in the brain.

Authors:  A Lippoldt; K Fuxe; F C Luft
Journal:  J Mol Med (Berl)       Date:  2001-04       Impact factor: 4.599

Review 3.  Pregnancy and the endocrine regulation of the baroreceptor reflex.

Authors:  Virginia L Brooks; Roger A L Dampney; Cheryl M Heesch
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2010-05-26       Impact factor: 3.619

Review 4.  Comparative neuroanatomical aspects of the salt and water balance in birds and mammals.

Authors:  G Ramieri; G C Panzica
Journal:  J Endocrinol Invest       Date:  1989-01       Impact factor: 4.256

Review 5.  The role of neuropeptides in cardiovascular regulation.

Authors:  D Ganten; M Paul; R E Lang
Journal:  Cardiovasc Drugs Ther       Date:  1991-02       Impact factor: 3.727

6.  Intracellular production of adrenal renin in the fetal mouse. An immuno-electron microscopical study.

Authors:  Y Kon; Y Hashimoto; H Kitagawa; M Sugimura; K Murakami
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Review 7.  Circulating and tissue angiotensin systems.

Authors:  D J Campbell
Journal:  J Clin Invest       Date:  1987-01       Impact factor: 14.808

Review 8.  Involvement of insulin-regulated aminopeptidase in the effects of the renin-angiotensin fragment angiotensin IV: a review.

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Review 9.  Role of angiotensin III in hypertension.

Authors:  Annabelle Reaux-Le Goazigo; Xavier Iturrioz; Celine Fassot; Cedric Claperon; Bernard P Roques; Catherine Llorens-Cortes
Journal:  Curr Hypertens Rep       Date:  2005-04       Impact factor: 5.369

10.  Endothelial production of C-type natriuretic peptide and its marked augmentation by transforming growth factor-beta. Possible existence of "vascular natriuretic peptide system".

Authors:  S Suga; K Nakao; H Itoh; Y Komatsu; Y Ogawa; N Hama; H Imura
Journal:  J Clin Invest       Date:  1992-09       Impact factor: 14.808
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