| Literature DB >> 6879177 |
S D Glick, P A Hinds, R M Shapiro.
Abstract
Cocaine elicited dose-related rotation (circling) in naïve rats. The maximum effect was greater than observed previously with other drugs. Overall, females were more sensitive to cocaine than males. However, right-biased females were more sensitive than left-biased females, whereas left-biased males were more sensitive than right-biased males. The results suggest that sex-dependent differences in brain asymmetry may be an important determinant of cocaine sensitivity.Entities:
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Year: 1983 PMID: 6879177 DOI: 10.1126/science.6879177
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728