Literature DB >> 6878903

Experimental retinal tolerance to liquid silicone.

R R Ober, J C Blanks, T E Ogden, M Pickford, D S Minckler, S J Ryan.   

Abstract

The effect of intraocular liquid silicone on the electroretinogram (ERG) and on retinal morphology was studied in rabbits. After vitrectomy, liquid silicone (1000 centistokes) or balanced salt solution (BSS) was injected into the eyes. The intraocular silicone was well tolerated clinically in all eyes that were followed over a period of 3 days to 6 months. ERG responses were equivalent in operated control and silicone-injected eyes. Light and electron microscopy showed slight but comparable changes in both operated control and silicone-injected eyes that were consistent with either fixation artifact and/or surgical trauma. The results suggest that exposure to silicone for up to 6 months does not have a toxic effect on the rabbit retina.

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Year:  1983        PMID： 6878903     DOI： 10.1097/00006982-198300320-00002

Source DB:  PubMed          Journal:  Retina        ISSN： 0275-004X            Impact factor:   4.256


  16 in total

1.  Electrophysiological changes after 360 degrees retinotomy and macular translocation for subfoveal choroidal neovascularisation in age related macular degeneration.

Authors:  C Lüke; S Aisenbrey; M Lüke; G Marzella; K U Bartz-Schmidt; P Walter
Journal:  Br J Ophthalmol       Date:  2001-08       Impact factor: 4.638

2.  Electro-oculographic findings after 360 degrees retinotomy and macular translocation for subfoveal choroidal neovascularisation in age-related macular degeneration.

Authors:  Christoph Lüke; Nils Alteheld; Sabine Aisenbrey; Matthias Lüke; Karl Ulrich Bartz-Schmidt; Peter Walter; Bernd Kirchhof
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2003-08-23       Impact factor: 3.117

3.  Fluorosilicone oil for retinal detachment.

Authors:  J D Scott
Journal:  Br J Ophthalmol       Date:  1990-11       Impact factor: 4.638

4.  Identification of silicone oil in ocular tissues.

Authors:  A Ohira
Journal:  Br J Ophthalmol       Date:  2005-02       Impact factor: 4.638

5.  Quantitative analysis of the insulating effect of silicone oil on the electroretinogram.

Authors:  M J Doslak
Journal:  Med Biol Eng Comput       Date:  1989-05       Impact factor: 2.602

6.  Experimental retinal tolerance to very low viscosity silicone oil (100 cs) as a vitreous substitute compared to higher viscosity silicone oil (5000 cs).

Authors:  M Soheilian; G A Peyman; T Moritera; H Wafapoor
Journal:  Int Ophthalmol       Date:  1995       Impact factor: 2.031

7.  Vitrectomy and fluid/silicone-oil exchange for giant retinal tears: results at six months.

Authors:  P K Leaver; R J Cooling; E B Feretis; J S Lean; D McLeod
Journal:  Br J Ophthalmol       Date:  1984-06       Impact factor: 4.638

8.  Electroretinographic studies following vitrectomy and intraocular silicone oil injection.

Authors:  T A Meredith; D T Lindsey; H F Edelhauser; A I Goldman
Journal:  Br J Ophthalmol       Date:  1985-04       Impact factor: 4.638

9.  Peritoneal reaction to liquid silicone: an experimental study.

Authors:  R Champion; J Faulborn; S Bowald; P Erb
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1987       Impact factor: 3.117

10.  Regular silicone and fluorosilicone oil in the prevention of retinal detachment caused by experimental proliferative vitreoretinopathy.

Authors:  A Alghadyan; G A Peyman; C Fizer; M Tawakol; K R Liu; B Yue; J H Peace
Journal:  Int Ophthalmol       Date:  1988-01       Impact factor: 2.031
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