Literature DB >> 687667

Production of protein HC by human fetal liver explants.

L Tejler, S Eriksson, A Grubb, B Astedt.   

Abstract

Human fetal lever explants were found to secrete protein HC into the medium in molar amounts comparable to those of albumin, alpha 1-antitrypsin and orosomucoid. Incorporation of a radioactive amino acid from the medium into the secreted protein HC demonstrated de novo synthesis. The secreted protein HC had the same size and electrophoretic mobility as protein HC of plasma and urine and gave a reaction of immunochemical identity with the protein in these biological fluids.

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Year:  1978        PMID： 687667     DOI： 10.1016/0304-4165(78)90380-x

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  12 in total

1.  Localization of alpha 1-microglobulin (HC protein) in normal human tissues: an immunohistochemical study using monoclonal antibodies.

Authors:  P Bouic; C Vincent; J P Revillard
Journal:  Histochem J       Date:  1984-12

2.  Vitreous levels of oxidative stress biomarkers and the radical-scavenger α1-microglobulin/A1M in human rhegmatogenous retinal detachment.

Authors:  Martin Cederlund; Fredrik Ghosh; Karin Arnér; Sten Andréasson; Bo Akerström
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2012-07-25       Impact factor: 3.117

3.  Adsorption of serum alpha-1-microglobulin onto biomaterials.

Authors:  M Santin; M Cannas; M A Wassall; S P Denyer
Journal:  J Mater Sci Mater Med       Date:  1998-03       Impact factor: 3.896

4.  Human alpha 1-microglobulin levels in various body fluids.

Authors:  K Takagi; K Kin; Y Itoh; H Enomoto; T Kawai
Journal:  J Clin Pathol       Date:  1980-08       Impact factor: 3.411

5.  Human protein HC and its IgA complex are inhibitors of neutrophil chemotaxis.

Authors:  E Méndez; J L Fernández-Luna; A Grubb; F Leyva-Cobián
Journal:  Proc Natl Acad Sci U S A       Date:  1986-03       Impact factor: 11.205

6.  177Lu-PSMA-617 Therapy in Mice, with or without the Antioxidant α1-Microglobulin (A1M), Including Kidney Damage Assessment Using 99mTc-MAG3 Imaging.

Authors:  Amanda Kristiansson; Anders Örbom; Jonas Ahlstedt; Helena Karlsson; Wahed Zedan; Magnus Gram; Bo Åkerström; Sven-Erik Strand; Mohamed Altai; Joanna Strand; Oskar Vilhelmsson Timmermand
Journal:  Biomolecules       Date:  2021-02-10

7.  Up-regulation of A1M/α1-microglobulin in skin by heme and reactive oxygen species gives protection from oxidative damage.

Authors:  Magnus G Olsson; Maria Allhorn; Jörgen Larsson; Martin Cederlund; Katarina Lundqvist; Artur Schmidtchen; Ole E Sørensen; Matthias Mörgelin; Bo Akerström
Journal:  PLoS One       Date:  2011-11-11       Impact factor: 3.240

8.  Alpha 1-microglobulin (HC protein) in human hepatocellular carcinoma.

Authors:  C Vincent; M C Kew; P Bouic; M Flacher; J P Revillard
Journal:  Br J Cancer       Date:  1989-03       Impact factor: 7.640

9.  A1M Ameliorates Preeclampsia-Like Symptoms in Placenta and Kidney Induced by Cell-Free Fetal Hemoglobin in Rabbit.

Authors:  Åsa Nääv; Lena Erlandsson; Josefin Axelsson; Irene Larsson; Martin Johansson; Lena Wester-Rosenlöf; Matthias Mörgelin; Vera Casslén; Magnus Gram; Bo Åkerström; Stefan R Hansson
Journal:  PLoS One       Date:  2015-05-08       Impact factor: 3.240

10.  Ferryl Hemoglobin and Heme Induce A1-Microglobulin in Hemorrhaged Atherosclerotic Lesions with Inhibitory Function against Hemoglobin and Lipid Oxidation.

Authors:  Dávid Pethő; Tamás Gáll; Zoltán Hendrik; Annamária Nagy; Lívia Beke; Attila Péter Gergely; Gábor Méhes; Csaba Tóth; Magnus Gram; Bo Åkerström; György Balla; József Balla
Journal:  Int J Mol Sci       Date:  2021-06-22       Impact factor: 5.923
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