| Literature DB >> 687642 |
Abstract
The influence of 27 possible effectors, mostly bispyridinium salts, upon the dealkylation (aging) of soman-inhibited acetylcholinesterase (acetylcholine hydrolase, EC 3.1.1.7) was examined at pH 7.6 and 25 degrees C. In the absence of effectors, the rate constant of the aging process was 4.0. 10(-2) min-1. At 2 mM, the strongest inhibitor reduced the rate to 0.8. 10(-2) min-1, whereas it was raised to 8.2. 10(-2) min-1 by the most potent accelerator.Entities:
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Year: 1978 PMID： 687642 DOI： 10.1016/0005-2744(78)90243-7
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002