Literature DB >> 6874586

Leptomycins A and B, new antifungal antibiotics. II. Structure elucidation.

T Hamamoto, H Seto, T Beppu.   

Abstract

The structures of new antifungal antibiotics, leptomycins A and B produced by Streptomyces sp. ATS1287 were determined as described below (Fig. 1) on the basis of their spectral and chemical character. Leptomycins have unique structures which belong to the unsaturated, branched-chain fatty acids with delta-lactone rings at the end.

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Year:  1983        PMID： 6874586     DOI： 10.7164/antibiotics.36.646

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  24 in total

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2.  Regulation and function of nuclear IκBα in inflammation and cancer.

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Review 3.  Ran-dependent nuclear export mediators: a structural perspective.

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4.  Microbial conversion products of leptomycin B.

Authors:  M Kuhnt; F Bitsch; M Ponelle; J J Sanglier; Y Wang; B Wolff
Journal:  Appl Environ Microbiol       Date:  1998-02       Impact factor: 4.792

5.  In vivo and in vitro anticancer activity of the structurally novel and highly potent antibiotic CI-940 and its hydroxy analog (PD 114,721).

Authors:  B J Roberts; K L Hamelehle; J S Sebolt; W R Leopold
Journal:  Cancer Chemother Pharmacol       Date:  1986       Impact factor: 3.333

Review 6.  Nuclear export of proteins and drug resistance in cancer.

Authors:  Joel G Turner; Jana Dawson; Daniel M Sullivan
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Review 7.  Antifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug action.

Authors:  M E Cardenas; M C Cruz; M Del Poeta; N Chung; J R Perfect; J Heitman
Journal:  Clin Microbiol Rev       Date:  1999-10       Impact factor: 26.132

8.  SUMOylation regulates nuclear localization of Krüppel-like factor 5.

Authors:  James X Du; Agnieszka B Bialkowska; Beth B McConnell; Vincent W Yang
Journal:  J Biol Chem       Date:  2008-09-09       Impact factor: 5.157

9.  Human multiple myeloma cells are sensitized to topoisomerase II inhibitors by CRM1 inhibition.

Authors:  Joel G Turner; Douglas C Marchion; Jana L Dawson; Michael F Emmons; Lori A Hazlehurst; Peter Washausen; Daniel M Sullivan
Journal:  Cancer Res       Date:  2009-08-18       Impact factor: 12.701

10.  Cardiovirus Leader proteins bind exportins: Implications for virus replication and nucleocytoplasmic trafficking inhibition.

Authors:  Jessica J Ciomperlik; Holly A Basta; Ann C Palmenberg
Journal:  Virology       Date:  2015-10-19       Impact factor: 3.616
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