Literature DB >> 6874000

Comparison between dissociation and inhibition of association of DNA/anti-DNA complexes.

R J Smeenk, L A Aarden, C J van Oss.   

Abstract

A study was made of the increases in ionic strength (mu) and in pH that would effect: a) the inhibition of association of anti-double stranded (ds) DNA and dsDNA, and b) the dissociation of anti-dsDNA from dsDNA, with respect to high avidity as well as to low avidity human anti-dsDNA antibodies, using Crithidia luciliae kinetoplasts as a source of dsDNA. The results obtained appear to indicate that the electrostatic component of the antigen-antibody bond does not become stronger with time (for times spans less than 1 hr).

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Year:  1983        PMID: 6874000     DOI: 10.3109/08820138309066867

Source DB:  PubMed          Journal:  Immunol Commun        ISSN: 0090-0877


  4 in total

Review 1.  A comparison of assays used for the detection of antibodies to DNA.

Authors:  R Smeenk; K Brinkman; H van den Brink; T Swaak
Journal:  Clin Rheumatol       Date:  1990-03       Impact factor: 2.980

Review 2.  Antibodies to DNA in patients with systemic lupus erythematosus. Their role in the diagnosis, the follow-up and the pathogenesis of the disease.

Authors:  R Smeenk; K Brinkman; H van den Brink; R M Termaat; J Berden; H Nossent; T Swaak
Journal:  Clin Rheumatol       Date:  1990-03       Impact factor: 2.980

3.  The interaction of anti-DNA antibodies with DNA antigen: Evidence for hysteresis for high avidity binding.

Authors:  David S Pisetsky; Robert Shaffer; Dustin D Armstrong; Diane M Spencer
Journal:  Clin Immunol       Date:  2021-09-04       Impact factor: 10.190

4.  Murine monoclonal antibodies to DNA. A comparison of MRL/lpr NZB/W and chronically graft-versus-host-diseased mice.

Authors:  K Brinkman; A van Dam; H van den Brink; R M Termaat; J Berden; R Smeenk
Journal:  Clin Exp Immunol       Date:  1990-05       Impact factor: 4.330

  4 in total

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