Literature DB >> 6873243

A new anti-mycotic drug tioxaprofen and its uncoupling effect on isolated mitochondria.

K Kawai, R Watanabe, Y Nozawa, M Nozaki, K Tsurumi, H Fujimura.   

Abstract

An oxazole compound, tioxaprofen, exerted a strong anti-mycotic activity against Trichophyton mentagrophytes and T. rubrum, which were major dermatophytes from patients. It was found that tioxaprofen was a potent uncoupling agent of mitochondrial respiration.

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Year:  1983        PMID： 6873243     DOI： 10.1007/bf01990422

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  6 in total

1.  The respiratory chain and oxidative phosphorylation.

Authors:  B CHANCE; G R WILLIAMS
Journal:  Adv Enzymol Relat Subj Biochem       Date:  1956

2.  The enzymic hydrolysis of adenosine triphosphate by liver mitochondria. I. Activities at different pH values.

Authors:  D K MYERS; E C SLATER
Journal:  Biochem J       Date:  1957-12       Impact factor: 3.857

3.  The osmotic behavior and permeability to non-electrolytes of mitochondria.

Authors:  H TEDESCHI; D L HARRIS
Journal:  Arch Biochem Biophys       Date:  1955-09       Impact factor: 4.013

4.  Intracellular distribution of enzymes; the oxidation of octanoic acid by rat liver fractions.

Authors:  W C SCHNEIDER
Journal:  J Biol Chem       Date:  1948-10       Impact factor: 5.157

5.  Water uptake and extrusion by mitochondria in relation to oxidative phosphorylation.

Authors:  A L LEHNINGER
Journal:  Physiol Rev       Date:  1962-07       Impact factor: 37.312

6.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157
  6 in total
  1 in total

1.  The impairing effects of chaetochromin D on mitochondrial respiration and structure.

Authors:  S Mori; K Kawai; Y Nozawa; K Koyama; S Natori
Journal:  Mycotoxin Res       Date:  1993-09       Impact factor: 3.833
  1 in total

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