| Literature DB >> 6871840 |
Z Gibas, R Becher, A A Sandberg, J Limon, U Bregula, M Rochowska.
Abstract
The simultaneous presence of chromosome segments with and without sister chromatid differentiation (SCD) in the same metaphase was observed in a human melanoma cell line after BrdU incorporation for 48-72 hr. This phenomenon was related to the time of BrdU incorporation by the cells: i.e., it was not observed after exposure to BrdU for only 17-20 hr. It is proposed, therefore, that the unusual staining pattern is caused through reduced BrdU incorporation by the cells after completing the first division.Entities:
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Year: 1983 PMID： 6871840 DOI： 10.1016/0165-4608(83)90087-0
Source DB: PubMed Journal: Cancer Genet Cytogenet ISSN： 0165-4608