Literature DB >> 6870841

Separation of porphyrin isomers by high-performance liquid chromatography.

C K Lim, J M Rideout, D J Wright.   

Abstract

A reversed-phase gradient elution system is described for the simultaneous separation of the type I and type III isomers of 8-, 7-, 6-, 5- and 4-carboxylated porphyrins and isocoproporphyrins. The method, adaptable for isocratic and stepwise separation of individual groups of isomers, is also suitable for preparative isolation of pure porphyrins. The analyses of porphyrin isomers in the urine and faeces of porphyric patients are examples of applications.

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Year:  1983        PMID: 6870841      PMCID: PMC1154376          DOI: 10.1042/bj2110435

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  11 in total

1.  Differentiation of porphyria cutanea tarda symptomatica from other types of porphyria by measurement of isocoproporphyrin in faeces.

Authors:  G H Elder
Journal:  J Clin Pathol       Date:  1975-08       Impact factor: 3.411

2.  Macrocyclic intermediates in the biosynthesis of porphyrins.

Authors:  A H Jackson; H A Sancovich; A M Ferramola; N Evans; D E Games; S A Matlin; G H Elder; S G Smith
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1976-02-05       Impact factor: 6.237

3.  Abnormal excretion of the isomers of urinary coproporphyrin by patients with Dubin-Johnson syndrome in Israel.

Authors:  J Ben-Ezzer; C Rimington; M Shani; U Seligsohn; C Sheba; A Szeinberg
Journal:  Clin Sci       Date:  1971-01       Impact factor: 6.124

4.  High-performance liquid chromatography of coproporphyrin isomers.

Authors:  D J Wright; J M Rideout; C K Lim
Journal:  Biochem J       Date:  1983-02-01       Impact factor: 3.857

5.  Altered coproporhyrin-isomer excretion in patients with the Dubin-Johnson syndrome.

Authors:  P Koskelo; P Mustajoki
Journal:  Int J Biochem       Date:  1980

6.  The prophyrins of normal human urine, with a comparison of the excretion pattern in porphyria cutanea tarda.

Authors:  S G Smith; K R Rao; A H Jackson
Journal:  Int J Biochem       Date:  1980

7.  A radiochemical method for the measurement of coproporphyrinogen oxidase and the utilization of substrates other than coproporphyrinogen III by the enzyme from rat liver.

Authors:  G H Elder; J O Evans
Journal:  Biochem J       Date:  1978-01-01       Impact factor: 3.857

8.  Rotor's syndrome. A distinct inheritable pathophysiologic entity.

Authors:  A W Wolkoff; E Wolpert; F N Pascasio; I M Arias
Journal:  Am J Med       Date:  1976-02       Impact factor: 4.965

9.  Identification of a group of tetracarboxylate porphyrins, containing one acetate and three propionate -substituents, in faeces from patients with symptomatic cutaneous hepatic porphyria and from rats with porphyria due to hexachlorobenzene.

Authors:  G H Elder
Journal:  Biochem J       Date:  1972-02       Impact factor: 3.857

10.  Separation of the coprophorphyrin isomers I and III by thin-layer chromatography.

Authors:  E Schermuly; M Doss
Journal:  Z Klin Chem Klin Biochem       Date:  1975-07
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  11 in total

1.  Coexistent hereditary coproporphyria and congenital erythropoietic porphyria (Günther disease).

Authors:  Y Nordmann; D Amram; J C Deybach; L N Phung; D Lesbros
Journal:  J Inherit Metab Dis       Date:  1990       Impact factor: 4.982

2.  A novel point mutation in congenital erythropoietic porphyria in two members of Japanese family.

Authors:  K Tanigawa; M Bensidhoum; N Takamura; H Namba; S Yamashita; H de Verneuil; C Ged
Journal:  Hum Genet       Date:  1996-05       Impact factor: 4.132

3.  Action of uroporphyrinogen decarboxylase on uroporphyrinogen-III: a reassessment of the clockwise decarboxylation hypothesis.

Authors:  T D Lash
Journal:  Biochem J       Date:  1991-09-15       Impact factor: 3.857

4.  Decarboxylation of uroporphyrinogen III by erythrocyte uroporphyrinogen decarboxylase. Evidence for a random decarboxylation mechanism.

Authors:  J Luo; C K Lim
Journal:  Biochem J       Date:  1990-06-01       Impact factor: 3.857

5.  Pseudoporphyria associated with consumption of brewers' yeast.

Authors:  C K Lim; J M Rideout; T J Peters
Journal:  Br Med J (Clin Res Ed)       Date:  1984-06-02

6.  Isolation, sequencing and expression of cDNA sequences encoding uroporphyrinogen decarboxylase from tobacco and barley.

Authors:  H P Mock; L Trainotti; E Kruse; B Grimm
Journal:  Plant Mol Biol       Date:  1995-05       Impact factor: 4.076

7.  Familial porphyria cutanea tarda: characterization of seven novel uroporphyrinogen decarboxylase mutations and frequency of common hemochromatosis alleles.

Authors:  M Mendez; L Sorkin; M V Rossetti; K H Astrin; A M del C Batlle; V E Parera; G Aizencang; R J Desnick
Journal:  Am J Hum Genet       Date:  1998-11       Impact factor: 11.025

8.  Reduction of Uroporphyrinogen Decarboxylase by Antisense RNA Expression Affects Activities of Other Enzymes Involved in Tetrapyrrole Biosynthesis and Leads to Light-Dependent Necrosis.

Authors:  H. P. Mock; B. Grimm
Journal:  Plant Physiol       Date:  1997-04       Impact factor: 8.340

9.  Lead poisoning: clinical, biochemical, and haematological aspects of a recent outbreak.

Authors:  A Pagliuca; G J Mufti; D Baldwin; A N Lestas; R M Wallis; A J Bellingham
Journal:  J Clin Pathol       Date:  1990-04       Impact factor: 3.411

10.  Rat liver uroporphyrinogen III synthase has similar properties to the enzyme from Euglena gracilis, including absence of a requirement for a reversibly bound cofactor for activity.

Authors:  E Smythe; D C Williams
Journal:  Biochem J       Date:  1988-07-01       Impact factor: 3.857

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