Literature DB >> 6870343

Effects of aromatic retinoid (Ro 109359) on Langerhans' cells in lichen planus.

R A Fernandez-Bussy, D Schmitt, G Mauduit, J Thivolet.   

Abstract

Retinoids are used in the treatment of lichen planus (LP) disease, but their mechanism of action remains unknown. We studied the epidermal Langerhans' cells in four patients with chronic LP, before and after treatment with aromatic retinoids. This study uses a new technique of quantification and exploits two monoclonal antibodies-OKT 6 specific for Langerhans' cells and BL 2 specific for HLA-DR antigens. Our results show an increase in the number of dendritic epidermal cells after treatment with oral retinoids. The number of OKT 6-positive cells is greater than the number of BL 2-positive (HLA-DR) cells before and after treatment.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6870343     DOI： 10.1007/bf00412884

Source DB:  PubMed          Journal:  Arch Dermatol Res        ISSN： 0340-3696            Impact factor:   3.017


  17 in total

1.  Influence of vitamin A on immunological response.

Authors:  M Jurin; I F Tannock
Journal:  Immunology       Date:  1972-09       Impact factor: 7.397

2.  Investigation on Langerhans cells in pathological human epidermis.

Authors:  P Lisi
Journal:  Acta Derm Venereol       Date:  1973       Impact factor: 4.437

3.  A method for quantifying Langerhans cells in epidermal sheets of human and murine skin.

Authors:  J J Nordlund; A Ackles
Journal:  Tissue Antigens       Date:  1981-02

Review 4.  Retinoids, cancer, and the skin.

Authors:  P M Elias; M L Williams
Journal:  Arch Dermatol       Date:  1981-03

5.  New staining techniques for the Langerhans cell.

Authors:  L Juhlin; W B Shelley
Journal:  Acta Derm Venereol       Date:  1977       Impact factor: 4.437

6.  Lichen planus and chronic graft-versus-host reaction. In situ identification of immunocompetent cell phenotypes.

Authors:  M A Gomes; D S Schmitt; P Souteyrand; C Ohrt; J Brochier; J Thivolet
Journal:  J Cutan Pathol       Date:  1982-08       Impact factor: 1.587

7.  Phenotype of cells involved in mycosis fungoides and Sézary syndrome (blood and skin lesions): immunomorphological study with monoclonal antibodies.

Authors:  D Schmitt; P Souteyrand; J Brochier; J Czernielewski; J Thivolet
Journal:  Acta Derm Venereol       Date:  1982       Impact factor: 4.437

8.  Natural and perturbed distributions of Langerhans cells: responses to ultraviolet light, heterotopic skin grafting, and dinitrofluorobenzene sensitization.

Authors:  P R Bergstresser; G B Toews; J W Streilein
Journal:  J Invest Dermatol       Date:  1980-07       Impact factor: 8.551

9.  Tolerance or hypersensitivity to 2,4-dinitro-1-fluorobenzene: the role of Langerhans cell density within epidermis.

Authors:  J W Streilein; G T Toews; J N Gilliam; P R Bergstresser
Journal:  J Invest Dermatol       Date:  1980-05       Impact factor: 8.551

10.  Effect of glucocorticosteroids on epidermal Langerhans cells.

Authors:  D V Belsito; T J Flotte; H W Lim; R L Baer; G J Thorbecke; I Gigli
Journal:  J Exp Med       Date:  1982-01-01       Impact factor: 14.307
View more
  2 in total

Review 1.  Does neoplasia in-situ develop due to the interaction of Epstein-Barr virus or herpes simplex virus-2 with Langerhans cells in the epithelium?

Authors:  Y Becker
Journal:  Virus Genes       Date:  1988-07       Impact factor: 2.332

2.  Distribution of Langerhans cells in skin lesions of MRL/l mice.

Authors:  H Kanauchi; F Furukawa; Y Horiguchi; T Horio; S Imamura
Journal:  Arch Dermatol Res       Date:  1988       Impact factor: 3.017
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.