Literature DB >> 6869971

Pasteurella haemolytica cytotoxin: production by recognized serotypes and neutralization by type-specific rabbit antisera.

P E Shewen, B N Wilkie.   

Abstract

A sterile culture supernatant from each of the 12 recognized serotypes of Pasteurella haemolytica was toxic to bovine alveolar macrophages when assayed by 51Cr release. Types appeared to differ in their ability to liberate cytotoxin, although this may have reflected strain variation rather than serotype-related differences. Toxicity was partially neutralized by type-specific rabbit antisera, with neutralization of the homologous toxin being more effective than that of the heterologous serotype.

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Year:  1983        PMID: 6869971

Source DB:  PubMed          Journal:  Am J Vet Res        ISSN: 0002-9645            Impact factor:   1.156


  14 in total

1.  Pulmonary immunity in calves following stimulation of the gut-associated lymphatic tissue by bacterial exotoxin.

Authors:  T L Bowersock; R D Walker; M L Samuels; R N Moore
Journal:  Can J Vet Res       Date:  1992-04       Impact factor: 1.310

2.  Use of 51Cr release to measure the cytotoxic effects of staphylococcal leukocidin and toxin neutralization on bovine leukocytes.

Authors:  D A Loeffler; K A Schat; N L Norcross
Journal:  J Clin Microbiol       Date:  1986-03       Impact factor: 5.948

3.  Vaccination of calves with leukotoxic culture supernatant from Pasteurella haemolytica.

Authors:  P E Shewen; B N Wilkie
Journal:  Can J Vet Res       Date:  1988-01       Impact factor: 1.310

4.  Molecular analysis of the leukotoxin determinants from Pasteurella haemolytica serotypes 1 to 16.

Authors:  L L Burrows; E Olah-Winfield; R Y Lo
Journal:  Infect Immun       Date:  1993-12       Impact factor: 3.441

5.  Proteolysis of sialoglycoprotein by Pasteurella haemolytica cytotoxic culture supernatant.

Authors:  G L Otulakowski; P E Shewen; A E Udoh; A Mellors; B N Wilkie
Journal:  Infect Immun       Date:  1983-10       Impact factor: 3.441

6.  Anticytotoxin activity of bovine sera and body fluids against Pasteurella haemolytica A1 cytotoxin.

Authors:  H J Cho; J G Bohac; W D Yates; H Bielefeldt Ohmann
Journal:  Can J Comp Med       Date:  1984-04

7.  Serological titers to bovine herpesvirus 1, bovine viral diarrhea virus, parainfluenza 3 virus, bovine respiratory syncytial virus and Pasteurella haemolytica in feedlot calves with respiratory disease: associations with bacteriological and pulmonary cytological variables.

Authors:  J W Allen; L Viel; K G Bateman; E Nagy; S Røsendal; P E Shewen
Journal:  Can J Vet Res       Date:  1992-10       Impact factor: 1.310

8.  Simple visual assay for determination of Pasteurella haemolytica cytotoxin neutralizing antibody titers in cattle sera.

Authors:  M J Gentry; A W Confer; J A Kreps
Journal:  J Clin Microbiol       Date:  1985-12       Impact factor: 5.948

9.  Pasteurella haemolytica cytotoxin neutralizing activity in sera from Ontario beef cattle.

Authors:  P E Shewen; B N Wilkie
Journal:  Can J Comp Med       Date:  1983-10

10.  Characterization of a neutralizing monoclonal antibody to Pasteurella haemolytica leukotoxin.

Authors:  D G Gerbig; M R Cameron; D K Struck; R N Moore
Journal:  Infect Immun       Date:  1992-05       Impact factor: 3.441

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