Literature DB >> 6869317

Phase II trial of 10-deaza-aminopterin in patients with advanced colorectal cancer.

E W Cheng, V E Currie, A Yagoda.   

Abstract

Twenty-two patients with advanced colorectal cancer were treated with 10-deaza-aminopterin given intravenously twice weekly for four doses beginning at 15 mg/m2. Twelve patients had no prior chemotherapy. Dose-limiting toxicity was mucositis. Tumor regression was not seen in any patient.

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Year:  1983        PMID: 6869317     DOI: 10.1097/00000421-198308000-00013

Source DB:  PubMed          Journal:  Am J Clin Oncol        ISSN: 0277-3732            Impact factor:   2.339


  1 in total

1.  Controlled trial of methotrexate versus 10-deazaaminopterin in the treatment of rheumatoid arthritis.

Authors:  G S Alarcón; O Castañeda; M G Nair; M Ferrándiz; W J Koopman; C L Krumdieck
Journal:  Ann Rheum Dis       Date:  1992-05       Impact factor: 19.103

  1 in total

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