Literature DB >> 6868971

Evidence of a possible direct action of Danazol on the human ovary.

A Milwidsky, N F Besch, P K Besch, R H Kaufman.   

Abstract

Strong evidence is presented that Danazol might exert a direct action on the human ovary by binding to receptor-like receptors for progesterone and testosterone, in concentrations well within the pharmacological range of the treated patient. The possible significance of this finding in understanding Danazol's mode of action is discussed.

Entities:  

Keywords:  Androgens; Biology; Clinical Research; Economic Factors; Endocrine System; Genitalia; Genitalia, Female; Hormone Receptors; Hormones; In Vitro; Membrane Proteins; Ovary; Physiology; Progestational Hormones; Progesterone; Prostaglandins; Prostaglandins, Synthetic; Research And Development; Research Methodology; Technology; Testosterone; Urogenital System

Mesh:

Substances:

Year:  1983        PMID: 6868971     DOI: 10.3109/00016348309155789

Source DB:  PubMed          Journal:  Acta Obstet Gynecol Scand        ISSN: 0001-6349            Impact factor:   3.636


  1 in total

1.  Effects of danazol on steroidogenesis and gonadotropic responsiveness in isolated human preovulatory follicular cells.

Authors:  J H Olsson; B Dennefors; L Nilsson
Journal:  J Endocrinol Invest       Date:  1986-04       Impact factor: 4.256

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.