Literature DB >> 6868339

A low molecular weight immunosuppressive factor produced by Onchocerca gibsoni.

D Yin Foo, M Nowak, B Copeman, M Mc Cabe.   

Abstract

An immunosuppressive factor(s) which is heat stable, and dialysable, with a molecular weight less than 10,000 molecular weight, and is not species specific, has been shown to be produced during the in vitro culture of Onchocerca gibsoni microfilariae. The factor(s) is capable of abolishing lymphocyte mitogenesis induced by Con A in bovine lymphocytes and PHA in human lymphocytes. The factor(s) may play a role in establishing the microfilariae in the tissues of the host by depressing cell mediated immune reactions during invasion.

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Year:  1983        PMID： 6868339     DOI： 10.1016/0165-2427(83)90004-1

Source DB:  PubMed          Journal:  Vet Immunol Immunopathol        ISSN： 0165-2427            Impact factor:   2.046


  6 in total

1.  The implantation of Taenia solium metacestodes in mice induces down-modulation of T-cell proliferation and cytokine production.

Authors:  Lilian Hernández-Mendoza; José Luis Molinari; Esperanza Garrido; Isabel Cortés; Sandra Solano; Enrique Miranda; Patricia Tato
Journal:  Parasitol Res       Date:  2005-01-28       Impact factor: 2.289

2.  Suppression of antigen- and mitogen-induced proliferation of bovine lymphocytes by excretory-secretory products of Oesophagostomum radiatum.

Authors:  L C Gasbarre; R D Romanowski; F W Douvres
Journal:  Infect Immun       Date:  1985-05       Impact factor: 3.441

3.  A histocytochemical study of the macrophages present in tissue responses to adult Onchocerca volvulus.

Authors:  A J Gatrill; C D Mackenzie; J E McMahon; J F Williams; R H Guderian
Journal:  Histochem J       Date:  1987-09

4.  Evaluation of spleen lymphocyte responsiveness to a T-cell mitogen during early infection with larval Taenia taeniaeformis.

Authors:  T Letonja; C Hammerberg; G Schurig
Journal:  Parasitol Res       Date:  1987       Impact factor: 2.289

5.  Suppression of murine lymphocyte proliferation induced by a small RNA purified from the Taenia solium metacestode.

Authors:  P Tato; A M Castro; D Rodríguez; R Soto; F Arechavaleta; J L Molinari
Journal:  Parasitol Res       Date:  1995       Impact factor: 2.289

6.  Suppression of human lymphocyte responses to specific and non-specific stimuli in human onchocerciasis.

Authors:  M Y Elkhalifa; H W Ghalib; T Dafa'Alla; J F Williams
Journal:  Clin Exp Immunol       Date:  1991-12       Impact factor: 4.330
  6 in total

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