Literature DB >> 686088

Tissue concentrations of free amino acids in term human placentas.

A F Philipps, I R Holzman, C Teng, F C Battaglia.   

Abstract

Five human term placentas were analyzed for total free amino acid concentrations. Calculation of tissue fluid distribution via 14C-inulin space enabled an estimation of placental intracellular amino acid concentrations based upon cord and maternal plasma concentrations. Maximum and minimum estimates for amino acid concentration in intracellular water are given. Data are compared to concentrations in organs of various species. Taurine was present in the highest concentration (3.529 +/- 1.120 mumoles per gram wet weight). Glutamic and aspartic acids, alanine, glycine, and glutamine were all present in concentrations greater than 0.5 mumoles per gram wet weight.

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Year:  1978        PMID: 686088     DOI: 10.1016/s0002-9378(16)33136-2

Source DB:  PubMed          Journal:  Am J Obstet Gynecol        ISSN: 0002-9378            Impact factor:   8.661


  26 in total

1.  Effects of taurine depletion on human placental syncytiotrophoblast renewal and susceptibility to oxidative stress.

Authors:  Michelle Desforges; Hannah Whittaker; Etaoin Farmer; Colin P Sibley; Susan L Greenwood
Journal:  Adv Exp Med Biol       Date:  2015       Impact factor: 2.622

2.  Facilitated transporters mediate net efflux of amino acids to the fetus across the basal membrane of the placental syncytiotrophoblast.

Authors:  J K Cleal; J D Glazier; G Ntani; S R Crozier; P E Day; N C Harvey; S M Robinson; C Cooper; K M Godfrey; M A Hanson; R M Lewis
Journal:  J Physiol       Date:  2011-01-04       Impact factor: 5.182

Review 3.  Transport and metabolism of amino acids in placenta.

Authors:  Timothy R H Regnault; Barbra de Vrijer; Frederick C Battaglia
Journal:  Endocrine       Date:  2002-10       Impact factor: 3.633

4.  Foetal glutamate as a possible precursor of placental glutamine in the guinea pig.

Authors:  D L Bloxam; C F Tyler; M Young
Journal:  Biochem J       Date:  1981-08-15       Impact factor: 3.857

5.  Effect of taurine, L-glutamine and L-histidine addition in an amino acid glucose solution on the cellular bioavailability of zinc.

Authors:  B Harraki; P Guiraud; M H Rochat; H Faure; M J Richard; M Fussellier; A Favier
Journal:  Biometals       Date:  1994-07       Impact factor: 2.949

6.  Transport of taurine and its regulation by protein kinase C in the JAR human placental choriocarcinoma cell line.

Authors:  P Kulanthaivel; D R Cool; S Ramamoorthy; V B Mahesh; F H Leibach; V Ganapathy
Journal:  Biochem J       Date:  1991-07-01       Impact factor: 3.857

7.  Reduced placental taurine transporter (TauT) activity in pregnancies complicated by pre-eclampsia and maternal obesity.

Authors:  Michelle Desforges; Andrea Ditchfield; Chloe R Hirst; Claire Pegorie; Kathryn Martyn-Smith; Colin P Sibley; Susan L Greenwood
Journal:  Adv Exp Med Biol       Date:  2013       Impact factor: 2.622

Review 8.  The pregnant sheep as a model for human pregnancy.

Authors:  J S Barry; R V Anthony
Journal:  Theriogenology       Date:  2007-11-05       Impact factor: 2.740

9.  L-proline transport by brush border membrane vesicles prepared from human placenta.

Authors:  C A Boyd; E K Lund
Journal:  J Physiol       Date:  1981-06       Impact factor: 5.182

10.  Heterogeneity of L-alanine transport systems in brush-border membrane vesicles from rat placenta during late gestation.

Authors:  S R Alonso-Torre; M A Serrano; J M Medina; F Alvarado
Journal:  Biochem J       Date:  1992-11-15       Impact factor: 3.857

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