Literature DB >> 6860531

The effect of hyoscine butylbromide on the swallowing of capsules.

K S Channer, A Wolinski, B Kaye, J Virjee.   

Abstract

Hyoscine butylbromide (20 mg) given intravenously to 48 patients with normal oesophageal motility significantly reduced oesophageal transit of hard gelatin capsules when swallowed in the erect and supine positions with 15 ml and 60 ml water when compared to an age/sex matched group. Delayed capsule transit and possible failed or slowed drug absorption occurring as a consequence of anti-cholinergic drugs on the oesophagus, constitutes a new drug interaction.

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Year:  1983        PMID： 6860531      PMCID： PMC1427708          DOI： 10.1111/j.1365-2125.1983.tb02091.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  8 in total

1.  Effects of drugs on esophageal motility.

Authors:  J Christensen
Journal:  Arch Intern Med       Date:  1976-05

2.  Drug-induced oesophageal injury.

Authors:  F J Collins; H R Matthews; S E Baker; J M Strakova
Journal:  Br Med J       Date:  1979-06-23

3.  Clinical pharmacology and therapeutics of the oesophagus and the lower oesophageal sphincter.

Authors:  J J Misiewicz
Journal:  Postgrad Med J       Date:  1974-04       Impact factor: 2.401

4.  Strong MJ, Hendrix TR: Response of the human oesophagus to d-tubocurarine and atropine.

Authors:  P A Kantrowitz; C I Siegel
Journal:  Gut       Date:  1970-01       Impact factor: 23.059

5.  Where do all the tablets go?

Authors:  K T Evans; G M Roberts
Journal:  Lancet       Date:  1976-12-04       Impact factor: 79.321

6.  Effect of posture and drink volume on the swallowing of capsules.

Authors:  K S Channer; J Virjee
Journal:  Br Med J (Clin Res Ed)       Date:  1982-12-11

7.  The ability of patients to swallow capsules.

Authors:  K T Evans; G M Roberts
Journal:  J Clin Hosp Pharm       Date:  1981-09

8.  Efficacy of radiology of the esophagus for evaluation of dysphagia.

Authors:  D J Ott; W C Wu; D W Gelfand
Journal:  Gastrointest Radiol       Date:  1981
  8 in total
  4 in total

1.  Buscopan in oesophageal food bolus: is it really effective?

Authors:  S Basavaraj; K R Penumetcha; H R Cable; N Umapathy
Journal:  Eur Arch Otorhinolaryngol       Date:  2004-12-09       Impact factor: 2.503

2.  Effect of left atrial size on the oesophageal transit of capsules.

Authors:  K S Channer; J Bell; J P Virjee
Journal:  Br Heart J       Date:  1984-08

3.  The effect of glucagon on the swallowing of capsules.

Authors:  K S Channer; R Bolton; S Al-Hilli; R Nakielny; J P Virjee
Journal:  Br J Clin Pharmacol       Date:  1983-10       Impact factor: 4.335

4.  Extrapyramidal reactions with metoclopramide.

Authors:  D N Bateman; M D Rawlins; J M Simpson
Journal:  Br Med J (Clin Res Ed)       Date:  1985-10-05
  4 in total

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