Literature DB >> 6860143

On the histopathogenesis of rat forestomach carcinoma caused by aristolochic acid.

U Mengs.   

Abstract

The histopathogenesis of rat forestomach carcinoma induced experimentally with aristolochic acid was investigated. The intragastric administration of 10 mg/kg/day caused extensive necrosis of the squamous epithelium, followed by regeneration and hyperplasia, papilloma formation and ultimately by invasive squamous cell carcinoma.

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Year:  1983        PMID： 6860143     DOI： 10.1007/bf00333900

Source DB:  PubMed          Journal:  Arch Toxicol        ISSN： 0340-5761            Impact factor:   5.153


  37 in total

1.  ARISTOLOCHIC ACID INTOXICATION: A NEW TYPE OF IMPAIRMENT OF URINARY CONCENTRATING ABILITY.

Authors:  G PETERS; P R HEDWALL
Journal:  Arch Int Pharmacodyn Ther       Date:  1963-10-01

2.  [Vergleich der genotoxischen Aktivität von Aristolochiasäure in verschiedenen Testsystemen].

Authors:  O Schimmer; G Abel; G Robisch; W Göggelmann
Journal:  Planta Med       Date:  1982-07       Impact factor: 3.352

3.  Notes on twenty-two Spontaneous tumors in Wild Rats (M. Norvegicus).

Authors:  P G Woolley; W B Wherry
Journal:  J Med Res       Date:  1911-09

4.  [Isolation of aristolochic acid from two Madagascar Aristolochiaceae. Determination of its toxicity on vegetal cells. Comparison with animal cells (author's transl)].

Authors:  C Moretti; M Rideau; J C Chénieux; C Viel
Journal:  Planta Med       Date:  1979-04       Impact factor: 3.352

5.  Induction of cancer by 20-methylcholanthrene in different regions of the rat stomach.

Authors:  G N Arkhipov
Journal:  Cancer Res       Date:  1970-11       Impact factor: 12.701

6.  Induction of cancer of the glandular stomach in rats by 20-methylcholanthrene.

Authors:  G N Arkhipov
Journal:  Int J Cancer       Date:  1967-09-15       Impact factor: 7.396

7.  Carcinogenicity of N-nitrosoephedrine in rats.

Authors:  G Eisenbrand; R Preussmann; D Schmähl
Journal:  Cancer Lett       Date:  1978-08       Impact factor: 8.679

8.  Studies on N-butyl-N-nitrosourethan-induced cancers of the esophagus and the forestomach of rats.

Authors:  T Yasumoto
Journal:  Nihon Geka Hokan       Date:  1978-03-01

9.  [Kidney diseases caused by drugs].

Authors:  K G Thiele; R C Muehrcke; H Berning
Journal:  Dtsch Med Wochenschr       Date:  1967-09-08       Impact factor: 0.628

10.  Methylnitrosophenylurea--a highly carcinogenic compound.

Authors:  R Warzok; R Thust; J Mendel; H Schwarz; E M Blaufuss
Journal:  Cancer Lett       Date:  1978-05       Impact factor: 8.679
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  15 in total

1.  Acute toxicity of aristolochic acid in rodents.

Authors:  U Mengs
Journal:  Arch Toxicol       Date:  1987-02       Impact factor: 5.153

2.  Tumour induction in mice following exposure to aristolochic acid.

Authors:  U Mengs
Journal:  Arch Toxicol       Date:  1988       Impact factor: 5.153

3.  Aristolochic acid is mutagenic and recombinogenic in Drosophila genotoxicity tests.

Authors:  H Frei; F E Würgler; H Juon; C B Hall; U Graf
Journal:  Arch Toxicol       Date:  1985-01       Impact factor: 5.153

4.  Balkan endemic nephropathy and aristolochic acid I: an investigation into the role of soil and soil organic matter contamination, as a potential natural exposure pathway.

Authors:  Alexandra T Gruia; Camelia Oprean; Alexandra Ivan; Ada Cean; Mirabela Cristea; Lavinia Draghia; Roxana Damiescu; Nikola M Pavlovic; Virgil Paunescu; Calin A Tatu
Journal:  Environ Geochem Health       Date:  2017-12-29       Impact factor: 4.609

5.  Genetic loci that affect aristolochic acid-induced nephrotoxicity in the mouse.

Authors:  Thomas A Rosenquist
Journal:  Am J Physiol Renal Physiol       Date:  2011-03-23

Review 6.  Aristolochic acid-associated cancers: a public health risk in need of global action.

Authors:  Samrat Das; Shefali Thakur; Michael Korenjak; Viktoriya S Sidorenko; Felicia Fei-Lei Chung; Jiri Zavadil
Journal:  Nat Rev Cancer       Date:  2022-07-19       Impact factor: 69.800

7.  Renal toxicity of aristolochic acid in rats as an example of nephrotoxicity testing in routine toxicology.

Authors:  U Mengs; C D Stotzem
Journal:  Arch Toxicol       Date:  1993       Impact factor: 5.153

8.  Detoxification of aristolochic acid I by O-demethylation: less nephrotoxicity and genotoxicity of aristolochic acid Ia in rodents.

Authors:  Shinya Shibutani; Radha R Bonala; Thomas Rosenquist; Robert Rieger; Naomi Suzuki; Francis Johnson; Frederick Miller; Arthur P Grollman
Journal:  Int J Cancer       Date:  2010-09-01       Impact factor: 7.396

9.  Gene expression profiles distinguish the carcinogenic effects of aristolochic acid in target (kidney) and non-target (liver) tissues in rats.

Authors:  Tao Chen; Lei Guo; Lu Zhang; Leming Shi; Hong Fang; Yongming Sun; James C Fuscoe; Nan Mei
Journal:  BMC Bioinformatics       Date:  2006-09-06       Impact factor: 3.169

10.  Microarray platform consistency is revealed by biologically functional analysis of gene expression profiles.

Authors:  Zhiguang Li; Zhenqiang Su; Zhining Wen; Leming Shi; Tao Chen
Journal:  BMC Bioinformatics       Date:  2009-10-08       Impact factor: 3.169
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