Literature DB >> 6858542

The effect of glucagon on the glycosaminoglycan content of canine arteries.

O V Sirek, A Sirek, E Cukerman.   

Abstract

Hypophysectomized young beagles were treated for 21 days with pharmacological doses of glucagon, administered intramuscularly in two daily injections of 0.5 mg each. Hyaluronic acid, heparan, dermatan and isomeric chondroitin sulphates were determined in aorta, carotid, iliac, renal, mesenteric and coronary arteries. In comparison with age-matched hypophysectomized controls, glucagon-treated dogs showed a reduction in the heparan sulphate concentration in their carotid arteries and thoracic aorta. These results indicate that glucagon has a very limited effect on arterial glycosaminoglycan content.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6858542     DOI： 10.1007/bf02629125

Source DB:  PubMed          Journal:  Acta Diabetol Lat        ISSN： 0001-5563


  10 in total

1.  The effect of sex hormones on glycosaminoglycan content of canine aorta and coronary arteries.

Authors:  O V Sirek; A Sirek; K Fikar
Journal:  Atherosclerosis       Date:  1977-06       Impact factor: 5.162

2.  Action of growth hormone and thyroxine on aortas of hypophysectomized dogs.

Authors:  M E Brosnan; O V Sirek; A Sirek; K Przybylska
Journal:  Diabetes       Date:  1973-04       Impact factor: 9.461

3.  Effect of pancreatectomy, with and without hypophysectomy, and of insulin treatment on the composition of canine aorta.

Authors:  M E Brosnan; O V Sirek; A Sirek; K Przybylska
Journal:  Diabetes       Date:  1973-05       Impact factor: 9.461

4.  Microanalysis and characterization of acidic glycosaminoglycans in human tissues.

Authors:  M Breen; H G Weinstein; M Andersen; A Veis
Journal:  Anal Biochem       Date:  1970-05       Impact factor: 3.365

5.  Relationship of plasma insulin levels to the incidence of myocardial infarction and coronary heart disease mortality in a middle-aged population.

Authors:  P Ducimetiere; E Eschwege; L Papoz; J L Richard; J R Claude; G Rosselin
Journal:  Diabetologia       Date:  1980-09       Impact factor: 10.122

6.  Intermittent hyperinsulinaemia and arterial glycosaminoglycans in dogs.

Authors:  O V Sirek; A Sirek; E Cukerman
Journal:  Diabetologia       Date:  1981-08       Impact factor: 10.122

7.  Lack of somatotropin effect on glycosaminoglycan content of canine coronary arteries.

Authors:  O V Sirek; A Sirek; K Fikar; K Przybylska
Journal:  Endocrinology       Date:  1976-12       Impact factor: 4.736

Review 8.  Role of glucagon in the pathogenesis of diabetes: the status of the controversy.

Authors:  R H Unger
Journal:  Metabolism       Date:  1978-11       Impact factor: 8.694

9.  Arterial glycosaminoglycans in diabetic dogs.

Authors:  O V Sirek; A Sirek; E Cukerman
Journal:  Blood Vessels       Date:  1980

10.  Effect of hormones on the glycosaminoglycan content of canine renal arteries.

Authors:  O V Sirek; A Sirek; E Cukerman
Journal:  Blood Vessels       Date:  1978
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.