Literature DB >> 6857761

Isolation and amino acid compositions of geographutoxin I and II from the marine snail Conus geographus.

H Nakamura, J Kobayashi, Y Ohizumi, Y Hirata.   

Abstract

The peptide toxins having inhibitory effects on the contractile response of the mouse diaphragm to direct stimulation, geographutoxin I and II, have been isolated from Conus geographus, and their amino acid compositions have been determined.

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Year:  1983        PMID: 6857761     DOI: 10.1007/bf01971110

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  8 in total

1.  Cone shell stings; recent cases of human injury due to venomous marine snails of the genus Conus.

Authors:  A J KOHN
Journal:  Hawaii Med J       Date:  1958 Jul-Aug

2.  Pharmacology of the venom of Conus geographus.

Authors:  R Endean; G Parish; P Gyr
Journal:  Toxicon       Date:  1974-03       Impact factor: 3.033

3.  Peptides isolated from the venom of Conus geographus block neuromuscular transmission.

Authors:  O B McManus; J R Musick; C Gonzalez
Journal:  Neurosci Lett       Date:  1981-08-07       Impact factor: 3.046

4.  Purification and properties of a myotoxin from Conus geographus venom.

Authors:  L J Cruz; W R Gray; B M Olivera
Journal:  Arch Biochem Biophys       Date:  1978-10       Impact factor: 4.013

5.  Peptide toxins from Conus geographus venom.

Authors:  W R Gray; A Luque; B M Olivera; J Barrett; L J Cruz
Journal:  J Biol Chem       Date:  1981-05-25       Impact factor: 5.157

6.  Pharmacological study on the venom of the marine snail Conus textile.

Authors:  J Kobayashi; Y Ohizumi; H Nakamura; Y Hirata
Journal:  Toxicon       Date:  1981       Impact factor: 3.033

7.  Effect of venoms from Conidae on skeletal, cardiac and smooth muscles.

Authors:  J Kobayashi; H Nakamura; Y Hirata; Y Ohizumi
Journal:  Toxicon       Date:  1982       Impact factor: 3.033

8.  Characterization of the neurotoxic constituents of Conus geographus (L) venom.

Authors:  I Spence; D Gillessen; R P Gregson; R J Quinn
Journal:  Life Sci       Date:  1977-12-15       Impact factor: 5.037

  8 in total
  8 in total

1.  Novel interactions identified between micro -Conotoxin and the Na+ channel domain I P-loop: implications for toxin-pore binding geometry.

Authors:  Tian Xue; Irene L Ennis; Kazuki Sato; Robert J French; Ronald A Li
Journal:  Biophys J       Date:  2003-10       Impact factor: 4.033

2.  Use of geographutoxin II (mu-conotoxin) for the study of neuromuscular transmission in mouse.

Authors:  S J Hong; C C Chang
Journal:  Br J Pharmacol       Date:  1989-07       Impact factor: 8.739

3.  Preferential block of skeletal muscle sodium channels by geographutoxin II, a new peptide toxin from Conus geographus.

Authors:  M Kobayashi; C H Wu; M Yoshii; T Narahashi; H Nakamura; J Kobayashi; Y Ohizumi
Journal:  Pflugers Arch       Date:  1986-08       Impact factor: 3.657

4.  [Venomous animals and their venoms].

Authors:  G G Habermehl; H C Krebs
Journal:  Naturwissenschaften       Date:  1986-08

5.  E.E. Just Lecture, 1996. Conus venom peptides, receptor and ion channel targets, and drug design: 50 million years of neuropharmacology.

Authors:  B M Olivera
Journal:  Mol Biol Cell       Date:  1997-11       Impact factor: 4.138

6.  Conotoxin GIIIA: selective inhibition of 22Na influx via voltage-dependent Na channels in adrenal medullary cells.

Authors:  A Wada; Y Uezono; M Arita; Y Yanagawa; M Satake; F Izumi
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1990-09       Impact factor: 3.000

7.  Geographutoxin-sensitive and insensitive sodium currents in mouse skeletal muscle developing in situ.

Authors:  T Gonoi; Y Hagihara; J Kobayashi; H Nakamura; Y Ohizumi
Journal:  J Physiol       Date:  1989-07       Impact factor: 5.182

8.  Pore residues critical for mu-CTX binding to rat skeletal muscle Na+ channels revealed by cysteine mutagenesis.

Authors:  R A Li; R G Tsushima; R G Kallen; P H Backx
Journal:  Biophys J       Date:  1997-10       Impact factor: 4.033

  8 in total

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