Literature DB >> 6857258

Serum factor supporting long-term survival of rat central neurons in culture.

L M Kaufman, J N Barrett.   

Abstract

Gel filtration of serum at pH 3.6 yielded a fraction that supported long-term (months) survival of dissociated rat central neurons in monolayer culture more reliably than the traditionally used unfractionated serum. The cultures remained neuron-rich, because this fraction did not support the proliferation of glia and fibroblasts that occurs in whole serum. With an apparent molecular weight of 55,000 and an isoelectric point of 5.6, the active factor (or factors) in this fraction is distinct from any well-defined growth factor.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6857258     DOI： 10.1126/science.6857258

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  16 in total

1.  Neuronal and ependymal expression of selenoprotein P in the human brain.

Authors:  M Scharpf; U Schweizer; T Arzberger; W Roggendorf; L Schomburg; J Köhrle
Journal:  J Neural Transm (Vienna)       Date:  2007-01-25       Impact factor: 3.575

2.  Peripheral nerve extract promotes long-term survival and neurite outgrowth in cultured spinal cord neurons.

Authors:  H Popiela; T Porter; R L Beach; B W Festoff
Journal:  Cell Mol Neurobiol       Date:  1984-03       Impact factor: 5.046

3.  Pyroptotic neuronal cell death mediated by the AIM2 inflammasome.

Authors:  Stephanie E Adamczak; Juan Pablo de Rivero Vaccari; Gordon Dale; Frank J Brand; Doris Nonner; M Ross Bullock; Gerhard P Dahl; W Dalton Dietrich; Robert W Keane
Journal:  J Cereb Blood Flow Metab       Date:  2014-01-08       Impact factor: 6.200

4.  5-Hydroxytryptamine 5HT2C receptors form a protein complex with N-methyl-D-aspartate GluN2A subunits and activate phosphorylation of Src protein to modulate motoneuronal depolarization.

Authors:  Gregory E Bigford; Nauman S Chaudhry; Robert W Keane; Alice M Holohean
Journal:  J Biol Chem       Date:  2012-01-30       Impact factor: 5.157

5.  Neurotrophin effects on survival and expression of cholinergic properties in cultured rat septal neurons under normal and stress conditions.

Authors:  D Nonner; E F Barrett; J N Barrett
Journal:  J Neurosci       Date:  1996-11-01       Impact factor: 6.167

6.  Overexpression of Cdk5 or non-phosphorylatable retinoblastoma protein protects septal neurons from oxygen-glucose deprivation.

Authors:  Kiran S Panickar; Doris Nonner; Michael G White; John N Barrett
Journal:  Neurochem Res       Date:  2008-03-20       Impact factor: 3.996

7.  Tumor cell motility and metastasis : Autocrine motility factor as an example of ecto/exoenzyme cytokines.

Authors:  S Silletti; S Paku; A Raz
Journal:  Pathol Oncol Res       Date:  1997-09       Impact factor: 3.201

8.  Purification from bovine serum of a survival-promoting factor for cultured central neurons and its identification as selenoprotein-P.

Authors:  J Yan; J N Barrett
Journal:  J Neurosci       Date:  1998-11-01       Impact factor: 6.167

9.  Casein kinase II contributes to the synergistic effects of BMP7 and BDNF on Smad 1/5/8 phosphorylation in septal neurons under hypoglycemic stress.

Authors:  Florence Chaverneff; John Barrett
Journal:  J Neurochem       Date:  2009-02-13       Impact factor: 5.372

10.  Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration.

Authors:  Eva K Wirth; Marcus Conrad; Jochen Winterer; Christian Wozny; Bradley A Carlson; Stephan Roth; Dietmar Schmitz; Georg W Bornkamm; Vincenzo Coppola; Lino Tessarollo; Lutz Schomburg; Josef Köhrle; Dolph L Hatfield; Ulrich Schweizer
Journal:  FASEB J       Date:  2009-11-04       Impact factor: 5.191
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.