Literature DB >> 6857247

Mutations affecting programmed cell deaths in the nematode Caenorhabditis elegans.

E M Hedgecock, J E Sulston, J N Thomson.   

Abstract

Mutations in two nonessential genes specifically block the phagocytosis of cells programmed to die during development. With few exceptions, these cells still die, suggesting that, in nematodes, engulfment is not necessary for most programmed deaths. Instead, these deaths appear to occur by cell suicide.

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Year:  1983        PMID： 6857247     DOI： 10.1126/science.6857247

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  96 in total

1.  Listeria monocytogenes exploits normal host cell processes to spread from cell to cell.

Authors:  J R Robbins; A I Barth; H Marquis; E L de Hostos; W J Nelson; J A Theriot
Journal:  J Cell Biol       Date:  1999-09-20       Impact factor: 10.539

2.  Sequential action of Caenorhabditis elegans Rab GTPases regulates phagolysosome formation during apoptotic cell degradation.

Authors:  Pengfei Guo; Tianjing Hu; Juan Zhang; Shanya Jiang; Xiaochen Wang
Journal:  Proc Natl Acad Sci U S A       Date:  2010-10-04       Impact factor: 11.205

Review 3.  EGG molecules couple the oocyte-to-embryo transition with cell cycle progression.

Authors:  Jean M Parry; Andrew Singson
Journal:  Results Probl Cell Differ       Date:  2011

4.  Demonstration of the in vivo interaction of key cell death regulators by structure-based design of second-site suppressors.

Authors:  J Parrish; H Metters; L Chen; D Xue
Journal:  Proc Natl Acad Sci U S A       Date:  2000-10-24       Impact factor: 11.205

Review 5.  Cancer models in Caenorhabditis elegans.

Authors:  Natalia V Kirienko; Kumaran Mani; David S Fay
Journal:  Dev Dyn       Date:  2010-05       Impact factor: 3.780

Review 6.  Caenorhabditis elegans as an experimental tool for the study of complex neurological diseases: Parkinson's disease, Alzheimer's disease and autism spectrum disorder.

Authors:  Fernando Calahorro; Manuel Ruiz-Rubio
Journal:  Invert Neurosci       Date:  2011-11-08

Review 7.  Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells.

Authors:  Susan L Fink; Brad T Cookson
Journal:  Infect Immun       Date:  2005-04       Impact factor: 3.441

8.  Germline quality control: eEF2K stands guard to eliminate defective oocytes.

Authors:  Hsueh-Ping Chu; Yi Liao; James S Novak; Zhixian Hu; Jason J Merkin; Yuriy Shymkiv; Bart P Braeckman; Maxim V Dorovkov; Alexandra Nguyen; Peter M Clifford; Robert G Nagele; David E Harrison; Ronald E Ellis; Alexey G Ryazanov
Journal:  Dev Cell       Date:  2014-02-27       Impact factor: 12.270

9.  Caenorhabditis elegans genes required for the engulfment of apoptotic corpses function in the cytotoxic cell deaths induced by mutations in lin-24 and lin-33.

Authors:  Brendan D Galvin; Saechin Kim; H Robert Horvitz
Journal:  Genetics       Date:  2008-05-05       Impact factor: 4.562

Review 10.  Modeling molecular and cellular aspects of human disease using the nematode Caenorhabditis elegans.

Authors:  Gary A Silverman; Cliff J Luke; Sangeeta R Bhatia; Olivia S Long; Anne C Vetica; David H Perlmutter; Stephen C Pak
Journal:  Pediatr Res       Date:  2009-01       Impact factor: 3.756
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