| Literature DB >> 6856765 |
A A Luderer, N F Borrelli, J N Panzarino, G R Mansfield, D M Hess, J L Brown, E H Barnett, E W Hahn.
Abstract
Hyperthermia has been found to be a useful modality for cancer therapy. In this report, a biocompatible, ferrimagnetic glass-ceramic capable of inducing localized hyperthermia by hysteresis heating upon exposure to an alternating magnetic field is presented. When the glass-ceramic was placed in the region of a subcutaneously transplanted, weakly antigenic breast carcinoma and subjected to the magnetic field, sufficient temperature rise was obtained to cause significant (approximately 50%) tumor regrowth delay and a 12% permanent control. The data demonstrate that glass-ceramic-mediated hysteresis heating may be a useful therapeutic approach in the treatment of cancer which offers the advantage of producing a highly localized and predictable tumor volume hyperthermia.Entities:
Mesh：
Year: 1983 PMID： 6856765
Source DB: PubMed Journal: Radiat Res ISSN： 0033-7587 Impact factor: 2.841