Literature DB >> 6855472

The effects of aging on opioid modulation of feeding in rats.

B A Gosnell, A S Levine, J E Morley.   

Abstract

Feeding responses to naloxone and butorphanol tartrate were measured in Fisher-344 rats with ages of 2, 12, 22 and 28 months. The two younger groups were 10-100 times more sensitive than the older groups to the suppressive effects of naloxone on feeding. Additionally, the older rats were less responsive to the feeding enhancement following butorphanol injections. These results are consistent with reports of age-related changes in endogenous opioid systems.

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Year:  1983        PMID: 6855472     DOI: 10.1016/0024-3205(83)90401-0

Source DB:  PubMed          Journal:  Life Sci        ISSN: 0024-3205            Impact factor:   5.037


  13 in total

Review 1.  [Pathophysiology of catabolism in undernurished elderly patients].

Authors:  D Baez-Franceschi; J E Morley
Journal:  Z Gerontol Geriatr       Date:  1999-07       Impact factor: 1.281

Review 2.  Mechanisms of the anorexia of aging-a review.

Authors:  Adam Wysokiński; Tomasz Sobów; Iwona Kłoszewska; Tomasz Kostka
Journal:  Age (Dordr)       Date:  2015-08-01

Review 3.  Appetite regulation: the role of peptides and hormones.

Authors:  J E Morley
Journal:  J Endocrinol Invest       Date:  1989-02       Impact factor: 4.256

4.  Anorexia of aging: a true geriatric syndrome.

Authors:  J E Morley
Journal:  J Nutr Health Aging       Date:  2012-05       Impact factor: 4.075

5.  Assessment of malnutrition in older persons: a focus on the Mini Nutritional Assessment.

Authors:  J E Morley
Journal:  J Nutr Health Aging       Date:  2011-02       Impact factor: 4.075

6.  The effects of aging on day-night rhythms of kappa opiate-mediated feeding in the mouse.

Authors:  M Kavaliers; G C Teskey; M Hirst
Journal:  Psychopharmacology (Berl)       Date:  1985       Impact factor: 4.530

7.  Function and regulation of cholecystokinin octapeptide, beta-endorphin and gastrin in anorexic infantile rats treated with ErBao Granules.

Authors:  Y P Du; Y P Zhang; S C Wang; J Shi; S H Wu
Journal:  World J Gastroenterol       Date:  2001-04       Impact factor: 5.742

Review 8.  Anorexia in older persons: epidemiology and optimal treatment.

Authors:  J E Morley
Journal:  Drugs Aging       Date:  1996-02       Impact factor: 3.923

9.  Inflated reward value in early opiate withdrawal.

Authors:  Kate M Wassum; Venuz Y Greenfield; Kay E Linker; Nigel T Maidment; Sean B Ostlund
Journal:  Addict Biol       Date:  2014-07-31       Impact factor: 4.280

10.  Endocrine and metabolic changes in human aging.

Authors:  W A Banks; J E Morley
Journal:  J Am Aging Assoc       Date:  2000-04
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