Literature DB >> 685339

[The intestinal and diffuse type of the gastric carcinoma (author's transl)].

K Heilmann, H U Burkhardt, K Kayser.   

Abstract

According to the Laurén classification 357 carcinomas of the stomach were reclassified into intestinal and diffuse types. 58.2% were assigned to the intestinal type, 37.5% to the diffuse and 4% to a "mixed" group. There is obvious correlation between the intestinal type, the patients' advancing age and the incidence of chronic, atrophising gastritis with intestinal metaplasia. The diffuse type on the other hand occurs irrespective of gastric changes - mostly in younger persons. The intestinal type of gastric carcinoma frequently is found in risk areas where incidence is "epidemic" in nature; morphology and genetic origin seem to be gastric mucosa changes and intestinal metaplasia or dysplasia. Classifying gastric carcinoma according to Laurén (two groups) is also an appropriate method in our regions as was confirmed by the results we obtained; it is superior to the much more differentiated macro- and microscopic classifications used so far. Because of its simplicity, it is better suited for epidemiological and pathogenetic studies of the gastric carcinoma.

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Year:  1978        PMID: 685339

Source DB:  PubMed          Journal:  Z Gastroenterol        ISSN: 0044-2771            Impact factor:   2.000


  2 in total

1.  Crude and age-specific incidence of cancer of the stomach, colon, breast, and lung ascertained by autopsy frequency in the Heidelberg area from 1900 to 1975.

Authors:  K Kayser; H U Burkhardt
Journal:  J Cancer Res Clin Oncol       Date:  1980-01       Impact factor: 4.553

2.  Clinicopathological analysis of the intestinal type and diffuse type of gastric carcinoma.

Authors:  S Noda; K Soejima; K Inokuchi
Journal:  Jpn J Surg       Date:  1980-12
  2 in total

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