A modified isokinetic strengthening program for patients with severe hemophilia.

A modified isokinetic strengthening program for the knee flexors and extensors was evaluated in 32 patients with severe hemophilia. The program was effective in significantly strengthening the knee flexors and extensors; it did not increase the number of knee hemarthroses; and it could be done at home without special equipment. The greater increases in extensor and flexor strength among adolescents and adults were associated with less severe arthropathy, a 1 cm increase in thigh girth, and a greater number of days on which the exercises were done.