Literature DB >> 6852239

Neo-kyotorphin (Thr-Ser-Lys-Tyr-Arg), a new analgesic peptide.

Y Kiso, K Kitagawa, N Kawai, T Akita, H Takagi, H Amano, K Fukui.   

Abstract

The amino acid sequence of a newly isolated pentapeptide, neo-kyotorphin from bovine brain was synthetically verified to be Thr-Ser-Lys-Tyr-Arg corresponding to the C-terminal portion of hemoglobin alpha-chain. The synthetic neo-kyotorphin showed the dose-dependent analgesia in mice which was approximately equal to that of Leu-enkephalin.

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Year:  1983        PMID： 6852239     DOI： 10.1016/0014-5793(82)80621-2

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  2 in total

Review 1.  Hemoglobin-derived peptides as novel type of bioactive signaling molecules.

Authors:  Ivone Gomes; Camila S Dale; Kimbie Casten; Miriam A Geigner; Fabio C Gozzo; Emer S Ferro; Andrea S Heimann; Lakshmi A Devi
Journal:  AAPS J       Date:  2010-09-02       Impact factor: 4.009

2.  PACAP and Other Neuropeptide Targets Link Chronic Migraine and Opioid-induced Hyperalgesia in Mouse Models.

Authors:  Krishna D. B. Anapindi; Ning Yang; Elena V Romanova; Stanislav S Rubakhin; Alycia Tipton; Isaac Dripps; Zoie Sheets; Jonathan V Sweedler; Amynah A Pradhan
Journal:  Mol Cell Proteomics       Date:  2019-10-24       Impact factor: 5.911
  2 in total

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