Literature DB >> 6852191

Hepatic proline after bile duct ligation in rats.

T S Chen, C L Boesch, C M Leevy.   

Abstract

Since biliary hyperplasia of fascioliasis correlated with hepatic proline level, we examined the occurrence of a similar chemical stimulus during bile obstruction. Uptake of tritiated proline and glycine rose in both hepatocytes and a bile duct enriched cell fraction, following duct ligation in rats. The increased hepatic content of proline but not glycine suggests that proline has a role in post-obstructive biliary proliferation.

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Year:  1983        PMID: 6852191     DOI: 10.1007/bf01971108

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  10 in total

1.  A quantitative assessment of the structural changes the rat's liver following obstruction of the common bile duct.

Authors:  J M Johnstone; E G Lee
Journal:  Br J Exp Pathol       Date:  1976-02

2.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

3.  The isolation and characterization of a bile ductule cell population from normal and bile-duct ligated rat livers.

Authors:  A G Grant; B H Billing
Journal:  Br J Exp Pathol       Date:  1977-06

4.  An improved method for determining specific radioactivities of proline-14C and hydroxyproline-14C in collagen and in noncollagenous proteins.

Authors:  M Rojkind; E González
Journal:  Anal Biochem       Date:  1974-01       Impact factor: 3.365

5.  Collagen biosynthesis in cirrhotic rat liver slices a regulatory mechanism.

Authors:  M Rojkind; L Diaz de León
Journal:  Biochim Biophys Acta       Date:  1970-10-15

6.  Fasciola hepatica: azetidine inhibition of bile duct hyperplasia in the infected rat.

Authors:  K L Girotra; H Isseroff
Journal:  Exp Parasitol       Date:  1980-02       Impact factor: 2.011

7.  A simple and specific determination of glycine in biological samples.

Authors:  S Ohmori; M Ikeda; Y Watanabe; K Hirota
Journal:  Anal Biochem       Date:  1978-10-15       Impact factor: 3.365

8.  Fascioliasis: role of proline in bile duct hyperplasia.

Authors:  H Isseroff; J T Sawma; D Reino
Journal:  Science       Date:  1977-12-16       Impact factor: 47.728

9.  Collagen biosynthesis in liver disease of the alcoholic.

Authors:  T S Chen; C M Leevy
Journal:  J Lab Clin Med       Date:  1975-01

10.  The relationship between the free pool of proline and collagen content in human liver cirrhosis.

Authors:  D Kershenobich; F J Fierro; M Rojkind
Journal:  J Clin Invest       Date:  1970-12       Impact factor: 14.808

  10 in total

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