A difference in the nucleoli of Purkinje cells of the nodular lobe of the hamster cerebellum.

Purkinje cells of the hamster cerebellum typically contain a large, single, centrally located nucleolus. Strikingly different are Purkinje cells concentrated in the nodular cortex, which characteristically contain several small, pale-staining nucleoli, most of which are peripherally located, in contact with the nuclear envelope. These atypical cells are also smaller, their Nissl bodies stain less intensely, and their nuclear envelopes appear more invaginated. Functional differences are implicit.