| Literature DB >> 6848118 |
T K O'Brien, J A Kendra, H A Stephens, R A Knight, A J Barrett.
Abstract
NK cells from young normal mice are cytolytic in vitro for a virus-induced tumour cell line, YAC-1. Cytotoxicity is inhibited by the addition of unlabelled homologous YAC-1 cells and by regenerating bone marrow cells from the spleens of lethally irradiated, bone-marrow-grafted mice. Quiescent marrow from syngeneic and allogeneic mice produces little or no competition. This suggests that NK cells recognize, and may regulate, marrow progenitor cells.Entities:
Mesh：
Year: 1983 PMID： 6848118 DOI： 10.1111/j.1365-2141.1983.tb01998.x
Source DB: PubMed Journal: Br J Haematol ISSN： 0007-1048 Impact factor: 6.998