Literature DB >> 6847670

Spectroscopic evidence for the formation of a transient species during cytochrome P-450scc induced hydroperoxysterol-glycol conversions.

C Larroque, J E van Lier.   

Abstract

Spectroscopic analysis of the interaction of the epimeric 20-hydroperoxy derivatives of cholesterol with bovine adrenocortical cytochrome P-450scc preparations suggested the formation of a transient species. The intermediate was detected at 4 degrees C and characterized by a minimum at 412 nm in the difference spectrum.

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Year:  1983        PMID： 6847670     DOI： 10.1016/0006-291x(83)91513-9

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  1 in total

1.  Cholesterol hydroperoxides as substrates for cholesterol-metabolizing cytochrome P450 enzymes and alternative sources of 25-hydroxycholesterol and other oxysterols.

Authors:  Johan E van Lier; Natalia Mast; Irina A Pikuleva
Journal:  Angew Chem Int Ed Engl       Date:  2015-07-29       Impact factor: 15.336
  1 in total

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