Literature DB >> 684353

[A new model of experimental arthrosis: contusion of the cartilage. Experimental and clinical study].

P Gédéon, B Mazières, P Ficat.   

Abstract

The effects of a single contusion without surface disruption and without fracture of the patella were studied in 40 rabbits. Macroscopic observation as well as light and electromicroscopy revealed lesions comparable to those observed in patients with chondromalacia of the patella and arthrosis. Three successive stages can be distinguished: a degeneration of the chondrocytes, a temporary proliferative reaction and an extension of the degenerative lesions resulting in an arthrosis. This is therefore a new model of chondromalacia and experimental arthrosis which is comparable in every respect to what is observed in human traumatology.

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Year:  1978        PMID: 684353

Source DB:  PubMed          Journal:  Rev Rhum Mal Osteoartic        ISSN: 0035-2659


  2 in total

Review 1.  Animal models for osteoarthritis: processes, problems and prospects.

Authors:  K P Pritzker
Journal:  Ann Rheum Dis       Date:  1994-06       Impact factor: 19.103

2.  Posttraumatic disturbance of the ossification of the patella.

Authors:  U Müller
Journal:  Arch Orthop Trauma Surg       Date:  1979-07-31
  2 in total

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