Literature DB >> 6843189

Colorectal carcinomas have a characteristic ganglioside pattern.

P Fredman, O Nilsson, L Svennerholm, H Myrvold, B Persson, S Pettersson, J Holmgren, L Lindholm.   

Abstract

The gangliosides in six colorectal and two pancreatic carcinomas were examined. Their concentration in the primary tumour and the metastases was 5-10 fold higher than in normal colon mucosa. This increase involved the simple gangliosides, GM3 and GD3, as well as complex mono- and disialogangliosides. Some complex monosialogangliosides were detected in all the colorectal and pancreatic carcinomas but neither in normal colon mucosa and pancreas nor in kidney and lung carcinomas.

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Year:  1983        PMID： 6843189

Source DB:  PubMed          Journal:  Med Biol        ISSN： 0302-2137


  6 in total

1.  Mammalian sialyltransferase ST3Gal-II: its exchange sialylation catalytic properties allow labeling of sialyl residues in mucin-type sialylated glycoproteins and specific gangliosides.

Authors:  E V Chandrasekaran; Jun Xue; Jie Xia; Robert D Locke; Shilpa A Patil; Sriram Neelamegham; Khushi L Matta
Journal:  Biochemistry       Date:  2011-10-13       Impact factor: 3.162

2.  Apoptosis of human breast carcinoma cells in the presence of cis-platin and L-/D-PPMP: IV. Modulation of replication complexes and glycolipid: Glycosyltransferases.

Authors:  Patrick J Boyle; Rui Ma; Narendra Tuteja; Sipra Banerjee; Subhash Basu
Journal:  Glycoconj J       Date:  2006-05       Impact factor: 2.916

3.  Detection by monoclonal antibody of carbohydrate antigen CA 50 in serum of patients with carcinoma.

Authors:  J Holmgren; L Lindholm; B Persson; T Lagergård; O Nilsson; L Svennerholm; C M Rudenstam; B Unsgaard; F Yngvason; S Pettersson
Journal:  Br Med J (Clin Res Ed)       Date:  1984-05-19

4.  The detection of colorectal carcinomas with the use of CA-50 radioimmunoassay inhibition test.

Authors:  N A Habib; M J Hershman; L Papp; I Swift; R C Williamson; C B Wood
Journal:  Int J Colorectal Dis       Date:  1986-07       Impact factor: 2.571

5.  Immunoreactivity of the 14F7 Mab Raised against N-Glycolyl GM3 Ganglioside in Epithelial Malignant Tumors from Digestive System.

Authors:  Rancés Blanco; Enrique Rengifo; Mercedes Cedeño; Charles E Rengifo; Daniel F Alonso; Adriana Carr
Journal:  ISRN Gastroenterol       Date:  2010-12-02

6.  Apoptosis of human breast carcinoma cells in the presence of disialosyl gangliosides: II. Treatment of SKBR3 cells with GD3 and GD1b gangliosides.

Authors:  Rui Ma; Atanas Koulov; Christopher Moulton; Manju Basu; Sipra Banerjee; Holly Goodson; Subhash Basu
Journal:  Glycoconj J       Date:  2004       Impact factor: 3.009
  6 in total

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